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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H12O6
Molecular Weight 180.1559
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SORBOSE

SMILES

OC[C@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

InChIKey=BJHIKXHVCXFQLS-OTWZMJIISA-N
InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6+/m0/s1

HIDE SMILES / InChI

Description

Sorbose is a ketose belonging to the group of sugars known as monosaccharides. It has a sweetness that is equivalent to sucrose (table sugar). L-Sorbose was also regarded as an alternative sugar, as it didn’t induce hyperglycemia or insulinemia, but mice which were fed by this compound had adverse effects: increased organ weights (liver, kidney, hearts)

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
for mice: 200 g/kg diet
Route of Administration: Oral
In Vitro Use Guide
L-sorbose acts directly on dog erythrocytes to induce hemolysis. L-sorbose depresses lactate formation in dog hemolysates from glucose, mannose and fructose but not from glucose-6-phosphate and galactose, thus L-sorbose interacts with glycolysis at the level of the hexokinase.