Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H9N5O4 |
| Molecular Weight | 239.1882 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC2=C(N=CN2COCC(O)=O)C(=O)N1
InChI
InChIKey=MICNQLKUSOVNNG-UHFFFAOYSA-N
InChI=1S/C8H9N5O4/c9-8-11-6-5(7(16)12-8)10-2-13(6)3-17-1-4(14)15/h2H,1,3H2,(H,14,15)(H3,9,11,12,16)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| High serum concentrations of the acyclovir main metabolite 9-carboxymethoxymethylguanine in renal failure patients with acyclovir-related neuropsychiatric side effects: an observational study. | 2003 Jun |
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| Acyclovir-induced neuropsychosis successfully recovered after immediate hemodialysis in an end-stage renal disease patient. | 2007 Aug |
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| Development, evaluation and application of an isocratic high-performance liquid chromatography (HPLC) assay for the simultaneous determination of aciclovir and its metabolite 9-carboxymethoxymethylguanine in human serum and cerebrospinal fluid. | 2007 Jul |
|
| [Risk of CNS adverse effects of aciclovir and valaciclovir. Watch the renal function in treatment of herpes simplex and herpes zoster]. | 2007 Jun 13-26 |
|
| Influence of ALDH2 genetic polymorphisms on aciclovir pharmacokinetics following oral administration of valaciclovir in Japanese end-stage renal disease patients. | 2008 |
|
| Acyclovir nephrotoxicity: a case report highlighting the importance of prevention, detection, and treatment of acyclovir-induced nephropathy. | 2010 |
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N28227W35C
Created by
admin on Sat Dec 16 09:45:09 GMT 2023 , Edited by admin on Sat Dec 16 09:45:09 GMT 2023
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9-Carboxymethoxymethylguanine
Created by
admin on Sat Dec 16 09:45:09 GMT 2023 , Edited by admin on Sat Dec 16 09:45:09 GMT 2023
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DTXSID40230501
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admin on Sat Dec 16 09:45:09 GMT 2023 , Edited by admin on Sat Dec 16 09:45:09 GMT 2023
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135508007
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admin on Sat Dec 16 09:45:09 GMT 2023 , Edited by admin on Sat Dec 16 09:45:09 GMT 2023
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80685-22-9
Created by
admin on Sat Dec 16 09:45:09 GMT 2023 , Edited by admin on Sat Dec 16 09:45:09 GMT 2023
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PARENT (METABOLITE)
SUBSTANCE RECORD
