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Details

Stereochemistry ACHIRAL
Molecular Formula C8H9N5O4
Molecular Weight 239.1882
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 9-CARBOXYMETHOXYMETHYLGUANINE

SMILES

NC1=NC2=C(N=CN2COCC(O)=O)C(=O)N1

InChI

InChIKey=MICNQLKUSOVNNG-UHFFFAOYSA-N
InChI=1S/C8H9N5O4/c9-8-11-6-5(7(16)12-8)10-2-13(6)3-17-1-4(14)15/h2H,1,3H2,(H,14,15)(H3,9,11,12,16)

HIDE SMILES / InChI

Molecular Formula C8H9N5O4
Molecular Weight 239.1882
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Aciclovir and valaciclovir neurotoxicity in patients with renal failure.
2003 Dec
Development, evaluation and application of an isocratic high-performance liquid chromatography (HPLC) assay for the simultaneous determination of aciclovir and its metabolite 9-carboxymethoxymethylguanine in human serum and cerebrospinal fluid.
2007 Jul
[Risk of CNS adverse effects of aciclovir and valaciclovir. Watch the renal function in treatment of herpes simplex and herpes zoster].
2007 Jun 13-26
Influence of ALDH2 genetic polymorphisms on aciclovir pharmacokinetics following oral administration of valaciclovir in Japanese end-stage renal disease patients.
2008
Acyclovir nephrotoxicity: a case report highlighting the importance of prevention, detection, and treatment of acyclovir-induced nephropathy.
2010
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:45:09 UTC 2023
Edited
by admin
on Sat Dec 16 09:45:09 UTC 2023
Record UNII
N28227W35C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
9-CARBOXYMETHOXYMETHYLGUANINE
Systematic Name English
ACETIC ACID, ((2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHOXY)-
Systematic Name English
CMMG
Common Name English
ACETIC ACID, 2-((2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHOXY)-
Systematic Name English
Code System Code Type Description
FDA UNII
N28227W35C
Created by admin on Sat Dec 16 09:45:09 UTC 2023 , Edited by admin on Sat Dec 16 09:45:09 UTC 2023
PRIMARY
WIKIPEDIA
9-Carboxymethoxymethylguanine
Created by admin on Sat Dec 16 09:45:09 UTC 2023 , Edited by admin on Sat Dec 16 09:45:09 UTC 2023
PRIMARY
EPA CompTox
DTXSID40230501
Created by admin on Sat Dec 16 09:45:09 UTC 2023 , Edited by admin on Sat Dec 16 09:45:09 UTC 2023
PRIMARY
PUBCHEM
135508007
Created by admin on Sat Dec 16 09:45:09 UTC 2023 , Edited by admin on Sat Dec 16 09:45:09 UTC 2023
PRIMARY
CAS
80685-22-9
Created by admin on Sat Dec 16 09:45:09 UTC 2023 , Edited by admin on Sat Dec 16 09:45:09 UTC 2023
PRIMARY
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