Onvuzosiran

Approval Year

Name

Type

Language

Onvuzosiran

Official Name

English

O-[(2R,3S)-2-(hydroxymethyl)oxolan-3-yl] hydrogen all-P-ambo-3'-O-(2-{[(1-{17-[(2-acetamido-2-deoxy-?-D-galactopyranosyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl}-1H-1,2,3-triazol-4-yl)methyl]amino}-2-oxoethyl)-2'-O-(2-{bis[(1-{17-[(2-acetamido-2-deoxy-?

Preferred Name

English

onvuzosiran [INN]

Common Name

English

RNA, ([3?-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-?-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2?-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-?-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxahep

Common Name

English

Code System Code Type Description

FDA UNII

MC7ZD4X9KB

Created by admin on Wed Apr 02 20:34:26 GMT 2025 , Edited by admin on Wed Apr 02 20:34:26 GMT 2025

PRIMARY

CAS

2982817-49-0

Created by admin on Wed Apr 02 20:34:26 GMT 2025 , Edited by admin on Wed Apr 02 20:34:26 GMT 2025

PRIMARY

INN

13361

Created by admin on Wed Apr 02 20:34:26 GMT 2025 , Edited by admin on Wed Apr 02 20:34:26 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_2-1_7;1_9;1_14-1_22;2_1;2_3;2_5;2_7;2_9;2_11;2_13;2_15;2_17;2_19;2_21-2_23	29 / 46
2'-Fluoro-Ribose	1_8;1_10-1_13;2_2;2_4;2_6;2_8;2_10;2_12;2_14;2_16;2_18;2_20	15 / 46
	1_23	1 / 46
	1_1	1 / 46

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_3;1_22-1_23;2_2-2_3;2_22-2_23	8 / 44
Phosphate	1_4-1_21;2_4-2_21	36 / 44

ACTIVE MOIETY


					MC7ZD4X9KB

Onvuzosiran

SALT/SOLVATE (PARENT)


					T4XC2DH9BM

Onvuzosiran sodium