WAY-317538

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H25N3O2
Molecular Weight	339.4314
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(CCCCN1CCOCC1)NC2=CC=C(C=C2)C3=CN=CC=C3

InChI

InChIKey=XCHIZTUBUXZESJ-UHFFFAOYSA-N

InChI=1S/C20H25N3O2/c24-20(5-1-2-11-23-12-14-25-15-13-23)22-19-8-6-17(7-9-19)18-4-3-10-21-16-18/h3-4,6-10,16H,1-2,5,11-15H2,(H,22,24)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19223665

SEN12333 is a alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Neuronal acetylcholine receptor subunit alpha-7 14 Target ID: P36544 Gene ID: 1139\|\|\|89832 Gene Symbol: CHRNA7 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19223665	Agonist 2678		1.6 µM [EC50]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Neurodegenerative diseases 14 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19223665	Primary		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

SEN12333 was administered intraperitoneally at the doses of 1, 3, and 10 mg/kg.

Route of Administration: Intraperitoneal

In Vitro Use Guide

Unknown

Name

Type

Language

WAY-317538

Common Name

English

N-(4-(3-PYRIDINYL)PHENYL)-4-MORPHOLINEPENTANAMIDE

Systematic Name

English

4-MORPHOLINEPENTANAMIDE, N-(4-(3-PYRIDINYL)PHENYL)-

Systematic Name

English

SEN-12333

Common Name

English

Code System Code Type Description

PUBCHEM

45484303

Created by admin on Sat Dec 16 14:11:59 GMT 2023 , Edited by admin on Sat Dec 16 14:11:59 GMT 2023

PRIMARY

CAS

874450-44-9

Created by admin on Sat Dec 16 14:11:59 GMT 2023 , Edited by admin on Sat Dec 16 14:11:59 GMT 2023

PRIMARY

SCIFINDER

EPA CompTox

DTXSID30670437

Created by admin on Sat Dec 16 14:11:59 GMT 2023 , Edited by admin on Sat Dec 16 14:11:59 GMT 2023

PRIMARY

FDA UNII

M92TU1EZ75

Created by admin on Sat Dec 16 14:11:59 GMT 2023 , Edited by admin on Sat Dec 16 14:11:59 GMT 2023

PRIMARY

ACTIVE MOIETY


					M92TU1EZ75

WAY-317538

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/19223665

CNS Activity

Originator

Approval Year

Targets

Conditions

Approved Use

PubMed

Patents

Sample Use Guides

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19223665