Details
Stereochemistry | ACHIRAL |
Molecular Formula | C6H14N2O3 |
Molecular Weight | 162.187 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@H]1C[C@@H](N)[C@H](O)[C@@H](O)[C@@H]1O
InChI
InChIKey=DTFAJAKTSMLKAT-JDCCYXBGSA-N
InChI=1S/C6H14N2O3/c7-2-1-3(8)5(10)6(11)4(2)9/h2-6,9-11H,1,7-8H2/t2-,3+,4+,5-,6-
Approval Year
PubMed
Title | Date | PubMed |
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Identification of L-glutamine: 2-deoxy-scyllo-inosose aminotransferase required for the biosynthesis of butirosin in Bacillus circulans. | 2002 Aug |
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Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine. | 2002 Dec 7 |
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Sequence-specific recognition of the major groove of RNA by deoxystreptamine. | 2002 May 21 |
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First identification of Streptomyces genes involved in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics--genetic and evolutionary analysis of L-glutamine:2-deoxy-scyllo-inosose aminotransferase genes. | 2002 Nov |
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A new family of glucose-1-phosphate/glucosamine-1-phosphate nucleotidylyltransferase in the biosynthetic pathways for antibiotics. | 2005 Feb 16 |
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The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides. | 2005 Nov 15 |
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Size-specific ligands for RNA hairpin loops. | 2005 Sep 14 |
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Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) group. | 2006 Aug |
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Biochemical and thermodynamic characterization of compounds that bind to RNA hairpin loops: toward an understanding of selectivity. | 2006 Sep 12 |
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Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin. | 2007 Dec 12 |
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A convenient synthesis of orthogonally protected 2-deoxystreptamine (2-DOS) as an aminocyclitol scaffold for the development of novel aminoglycoside antibiotic derivatives against bacterial resistance. | 2008 Aug 21 |
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The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: genetic and biochemical evidence for the roles of two glycosyltransferases and a deacetylase. | 2008 Sep 21 |
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Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme. | 2010 May 18 |
Patents
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72447
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65069
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m4180
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2037-48-1
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28295
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DTXSID70942529
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M88VD0X96M
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156938
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SALT/SOLVATE (PARENT)
SUBSTANCE RECORD