Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H5N5O3 |
| Molecular Weight | 195.1356 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1N=NC2=C(N=CN2C1=O)C(O)=O
InChI
InChIKey=VVTMIOYTNALQAW-UHFFFAOYSA-N
InChI=1S/C6H5N5O3/c1-10-6(14)11-2-7-3(5(12)13)4(11)8-9-10/h2H,1H3,(H,12,13)
Approval Year
Sample Use Guides
Human cancer cell lines HCT-8, A549, MCF-7, Bel-7402, BGC-823, MV3, M14, two mouse melanoma cell lines B16 and B16-BL6, and three human glioma cell lines TJ899, SHG-44 and TJ905 (10(3) cells per well) were treated with different concentrations of temozolomide acid for 96 h. IC50 values measured in MTT assay were: 184.72 uM (MV4), 185.35 uM (B16), 222.92 uM (B16-B6), 36.21 uM (SHG-44). 76.41 uM (MCF-7), 86.90 uM (Bel-7402), 94.93 uM (HCT-8).
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113942-30-6
Created by
admin on Sat Dec 16 08:35:40 GMT 2023 , Edited by admin on Sat Dec 16 08:35:40 GMT 2023
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11830328
Created by
admin on Sat Dec 16 08:35:40 GMT 2023 , Edited by admin on Sat Dec 16 08:35:40 GMT 2023
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M35A7FW55W
Created by
admin on Sat Dec 16 08:35:40 GMT 2023 , Edited by admin on Sat Dec 16 08:35:40 GMT 2023
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DTXSID40150614
Created by
admin on Sat Dec 16 08:35:40 GMT 2023 , Edited by admin on Sat Dec 16 08:35:40 GMT 2023
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PRIMARY |
SUBSTANCE RECORD
