Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H4N2O3 |
Molecular Weight | 140.0969 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=NC=C(O)N=C1
InChI
InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N
InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)
Approval Year
PubMed
Title | Date | PubMed |
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Quantification of pyrazinamide and its metabolites in plasma by ionic-pair high-performance liquid chromatography. Implications for the separation mechanism. | 1998 Mar 20 |
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Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. | 2002 Jul |
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A novel mechanism underlies the hepatotoxicity of pyrazinamide. | 2013 Apr |
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Global Urine Metabolomics in Patients Treated with First-Line Tuberculosis Drugs and Identification of a Novel Metabolite of Ethambutol. | 2016 Apr |
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An improved LC-MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5-hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study. | 2016 Apr 1 |
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Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid. | 2018 Apr |
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DTXSID40188179
Created by
admin on Sat Dec 16 13:42:41 GMT 2023 , Edited by admin on Sat Dec 16 13:42:41 GMT 2023
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34604-60-9
Created by
admin on Sat Dec 16 13:42:41 GMT 2023 , Edited by admin on Sat Dec 16 13:42:41 GMT 2023
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161825
Created by
admin on Sat Dec 16 13:42:41 GMT 2023 , Edited by admin on Sat Dec 16 13:42:41 GMT 2023
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M2V0DP3ENP
Created by
admin on Sat Dec 16 13:42:41 GMT 2023 , Edited by admin on Sat Dec 16 13:42:41 GMT 2023
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PARENT (METABOLITE)
SUBSTANCE RECORD