Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.0969 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=NC=C(O)N=C1
InChI
InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N
InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.0969 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Determination of pyrazinamide and its main metabolites in rat urine by high-performance liquid chromatography. | 1997 Aug 1 |
|
| Quantification of pyrazinamide and its metabolites in plasma by ionic-pair high-performance liquid chromatography. Implications for the separation mechanism. | 1998 Mar 20 |
|
| Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. | 2002 Jul |
|
| A novel mechanism underlies the hepatotoxicity of pyrazinamide. | 2013 Apr |
|
| Global Urine Metabolomics in Patients Treated with First-Line Tuberculosis Drugs and Identification of a Novel Metabolite of Ethambutol. | 2016 Apr |
|
| An improved LC-MS/MS method for the simultaneous determination of pyrazinamide, pyrazinoic acid and 5-hydroxy pyrazinoic acid in human plasma for a pharmacokinetic study. | 2016 Apr 1 |
|
| Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid. | 2018 Apr |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 13:42:41 GMT 2023
by
admin
on
Sat Dec 16 13:42:41 GMT 2023
|
| Record UNII |
M2V0DP3ENP
|
| Record Status |
Validated (UNII)
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| Record Version |
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34604-60-9
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161825
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M2V0DP3ENP
Created by
admin on Sat Dec 16 13:42:41 GMT 2023 , Edited by admin on Sat Dec 16 13:42:41 GMT 2023
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| Related Record | Type | Details | ||
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