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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H31FO5S
Molecular Weight 450.563
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIMOBESONE ACETATE

SMILES

CSC(=O)[C@@]1(OC(C)=O)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C

InChI

InChIKey=NWJQIUPQBDVVLW-QZIXMDIESA-N
InChI=1S/C24H31FO5S/c1-13-10-18-17-7-6-15-11-16(27)8-9-21(15,3)23(17,25)19(28)12-22(18,4)24(13,20(29)31-5)30-14(2)26/h8-9,11,13,17-19,28H,6-7,10,12H2,1-5H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1

HIDE SMILES / InChI

Description

Timobesone is a topical corticosteroid and thiol ester derivative with anti-inflammatory activity.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Micellar solubilization of timobesone acetate in aqueous and aqueous propylene glycol solutions of nonionic surfactants.
1988-11
Patents

Patents

20060018937
2
Name Type Language
RS-85446-007
Preferred Name English
TIMOBESONE ACETATE
USAN   WHO-DD  
USAN  
Official Name English
ANDROSTA-1,4-DIENE-17-CARBOTHIOIC ACID, 17-(ACETYLOXY)-9-FLUORO-11-HYDROXY-16-METHYL-3-OXO-, S-METHYL ESTER, (11.BETA.,16.BETA.,17.ALPHA.)-
Common Name English
TIMOBESONE ACETATE [USAN]
Common Name English
S-Methyl 9-fluoro-11?,17-dihydroxy-16?-methyl-3-oxoandrosta-1,4-diene-17?-carbothioate, 17-acetate
Common Name English
Timobesone acetate [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C521
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
Code System Code Type Description
CAS
79578-14-6
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
EPA CompTox
DTXSID201000603
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
NCI_THESAURUS
C90957
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
PUBCHEM
10095308
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
SMS_ID
300000055362
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
MESH
C059452
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
USAN
U-42
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
FDA UNII
LGO8R495QW
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
ChEMBL
CHEMBL2107051
Created by admin on Mon Mar 31 17:34:04 GMT 2025 , Edited by admin on Mon Mar 31 17:34:04 GMT 2025
PRIMARY
ACTIVE MOIETY
Structure of TIMOBESONE
SUBSTANCE RECORD
Structure of TIMOBESONE ACETATE
NIH
NCATS
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