TIMOBESONE ACETATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H31FO5S
Molecular Weight	450.563
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@H](C)[C@](OC(C)=O)(C(=O)SC)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=NWJQIUPQBDVVLW-QZIXMDIESA-N

InChI=1S/C24H31FO5S/c1-13-10-18-17-7-6-15-11-16(27)8-9-21(15,3)23(17,25)19(28)12-22(18,4)24(13,20(29)31-5)30-14(2)26/h8-9,11,13,17-19,28H,6-7,10,12H2,1-5H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H31FO5S
Molecular Weight	450.563
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3247274

Timobesone is a topical corticosteroid and thiol ester derivative with anti-inflammatory activity.

Originator

Approval Year

PubMed

Title	Date	PubMed
Micellar solubilization of timobesone acetate in aqueous and aqueous propylene glycol solutions of nonionic surfactants.	1988 Nov	3247274

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:59:11 GMT 2023` Edited by `admin` on `Fri Dec 15 14:59:11 GMT 2023`
Record UNII	LGO8R495QW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIMOBESONE ACETATE

Official Name

English

ANDROSTA-1,4-DIENE-17-CARBOTHIOIC ACID, 17-(ACETYLOXY)-9-FLUORO-11-HYDROXY-16-METHYL-3-OXO-, S-METHYL ESTER, (11.BETA.,16.BETA.,17.ALPHA.)-

Common Name

English

TIMOBESONE ACETATE [USAN]

Common Name

English

RS-85446-007

Code

English

S-Methyl 9-fluoro-11β,17-dihydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17β-carbothioate, 17-acetate

Common Name

English

Timobesone acetate [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521