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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19F2N5O4
Molecular Weight 407.3714
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Inavolisib

SMILES

C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N4[C@@H](COC4=O)C(F)F)C(N)=O

InChI

InChIKey=SGEUNORSOZVTOL-CABZTGNLSA-N
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)24)25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26)/t9-,12-/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
0.038 nM [IC50]