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Details

Stereochemistry UNKNOWN
Molecular Formula C60H88N2O19
Molecular Weight 1141.3427
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 19
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEPARTRICIN A

SMILES

CNC1=CC=C(C=C1)C(=O)CC(O)CCC(C)C2OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC3(O)CC(O)C(C(CC(O[C@H]4O[C@@H](C)[C@H](O)[C@@H](N)[C@H]4O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\C2C)O3)C(=O)OC

InChI

InChIKey=GVEVTKSEPQUIJA-BXMMMMRLSA-N
InChI=1S/C60H88N2O19/c1-36-18-16-14-12-10-8-6-7-9-11-13-15-17-19-48(79-59-56(74)54(61)55(73)38(3)78-59)33-51-53(58(75)77-5)50(71)35-60(76,81-51)34-47(69)30-45(67)28-43(65)26-42(64)27-44(66)29-46(68)32-52(72)80-57(36)37(2)20-25-41(63)31-49(70)39-21-23-40(62-4)24-22-39/h6-19,21-24,36-38,41-43,45-48,50-51,53-57,59,62-65,67-69,71,73-74,76H,20,25-35,61H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t36?,37?,38-,41?,42?,43?,45?,46?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59+,60?/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Binding of mepartricin to sex hormones, a key factor of its activity on benign prostatic hyperplasia.
2001
Effects of mepartricin on estradiol and testosterone serum levels and on prostatic estrogen, androgen and adrenergic receptor concentrations in adult rats.
2001 Aug
[Mepartricine and prostatitis. Clinical experience and rationale for use].
2001 Sep
Effects of mepartricin on estradiol and testosterone serum levels and on prostatic estrogen, androgen and adrenergic receptor concentration in adult rats.
2002 Oct
[Thermal knowledge and therapies: a comparative view of Portugal (São Pedro do Sul hot springs) and Brazil (Caldas da Imperatriz hot springs)].
2004
Role of mepartricin in category III chronic nonbacterial prostatitis/chronic pelvic pain syndrome: a randomized prospective placebo-controlled trial.
2004 Jan
Effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic growth of the dorsolateral prostate and seminal vesicle in immature castrated rats.
2005
Mepartricin long-term administration regulates steroid hormone and adrenergic receptor concentrations in the prostate of aged rats.
2006 Aug
Management of chronic prostatitis/chronic pelvic pain syndrome: an evidence-based approach.
2006 May
Antifungal chemical compounds identified using a C. elegans pathogenicity assay.
2007 Feb
Chronic prostatitis.
2008 May 22
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.
2009 Sep 14
Name Type Language
MEPARTRICIN A
MI  
Common Name English
GEDAMYCIN METHYL ESTER
Common Name English
PARTRICIN A METHYL ESTER
Common Name English
CANDICIDIN D, 40-DEMETHYL-3,7-DIDEOXO-3,7-DIHYDROXY-N47-METHYL-5-OXO-, METHYL ESTER, CYCLIC 15,19-HEMIACETAL
Common Name English
MEPARTRICIN A [MI]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
263-584-8
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
MERCK INDEX
m7184
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY Merck Index
FDA UNII
L13V8793FQ
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
EPA CompTox
DTXSID40872304
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
CAS
62534-68-3
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
PUBCHEM
76969110
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY