MEPARTRICIN A

Details

Stereochemistry	UNKNOWN
Molecular Formula	C60H88N2O19
Molecular Weight	1141.3427
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 19
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC1=CC=C(C=C1)C(=O)CC(O)CCC(C)C2OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC3(O)CC(O)C(C(CC(O[C@H]4O[C@@H](C)[C@H](O)[C@@H](N)[C@H]4O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\C2C)O3)C(=O)OC

InChI

InChIKey=GVEVTKSEPQUIJA-BXMMMMRLSA-N

InChI=1S/C60H88N2O19/c1-36-18-16-14-12-10-8-6-7-9-11-13-15-17-19-48(79-59-56(74)54(61)55(73)38(3)78-59)33-51-53(58(75)77-5)50(71)35-60(76,81-51)34-47(69)30-45(67)28-43(65)26-42(64)27-44(66)29-46(68)32-52(72)80-57(36)37(2)20-25-41(63)31-49(70)39-21-23-40(62-4)24-22-39/h6-19,21-24,36-38,41-43,45-48,50-51,53-57,59,62-65,67-69,71,73-74,76H,20,25-35,61H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t36?,37?,38-,41?,42?,43?,45?,46?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59+,60?/m0/s1

HIDE SMILES / InChI

Molecular Formula	C60H88N2O19
Molecular Weight	1141.3427
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	5 / 19
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.	2009-09-14	19750012
Chronic prostatitis.	2008-05-22	19450305
Antifungal chemical compounds identified using a C. elegans pathogenicity assay.	2007-02	17274686
Mepartricin long-term administration regulates steroid hormone and adrenergic receptor concentrations in the prostate of aged rats.	2006-08	16846466
Management of chronic prostatitis/chronic pelvic pain syndrome: an evidence-based approach.	2006-05	16698346
Effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic growth of the dorsolateral prostate and seminal vesicle in immature castrated rats.	2005	16257836
Role of mepartricin in category III chronic nonbacterial prostatitis/chronic pelvic pain syndrome: a randomized prospective placebo-controlled trial.	2004-01	14751338
[Thermal knowledge and therapies: a comparative view of Portugal (São Pedro do Sul hot springs) and Brazil (Caldas da Imperatriz hot springs)].	2004	15449383
Effects of mepartricin on estradiol and testosterone serum levels and on prostatic estrogen, androgen and adrenergic receptor concentration in adult rats.	2002-10	12356083
[Mepartricine and prostatitis. Clinical experience and rationale for use].	2001-09	11723437
Effects of mepartricin on estradiol and testosterone serum levels and on prostatic estrogen, androgen and adrenergic receptor concentrations in adult rats.	2001-08	11516265
[Mepartricin in the treatment of male pelvic pain syndrome secondary to chronic nonbacterial prostatitis/prostatodynia].	2001-03	11346715
[Long-term therapy of benign prostatic hyperplasia. Our experience].	2001-03	11346714
Binding of mepartricin to sex hormones, a key factor of its activity on benign prostatic hyperplasia.	2001	11799846

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:37:03 GMT 2025` Edited by `admin` on `Mon Mar 31 20:37:03 GMT 2025`
Record UNII	L13V8793FQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MEPARTRICIN A

Common Name

English

CANDICIDIN D, 40-DEMETHYL-3,7-DIDEOXO-3,7-DIHYDROXY-N47-METHYL-5-OXO-, METHYL ESTER, CYCLIC 15,19-HEMIACETAL

Preferred Name

English

GEDAMYCIN METHYL ESTER

Common Name

English

PARTRICIN A METHYL ESTER

Common Name

English

MEPARTRICIN A [MI]

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

263-584-8