U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry UNKNOWN
Molecular Formula C60H88N2O19
Molecular Weight 1141.3427
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 19
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEPARTRICIN A

SMILES

CNC1=CC=C(C=C1)C(=O)CC(O)CCC(C)C2OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC3(O)CC(O)C(C(CC(O[C@H]4O[C@@H](C)[C@H](O)[C@@H](N)[C@H]4O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\C2C)O3)C(=O)OC

InChI

InChIKey=GVEVTKSEPQUIJA-BXMMMMRLSA-N
InChI=1S/C60H88N2O19/c1-36-18-16-14-12-10-8-6-7-9-11-13-15-17-19-48(79-59-56(74)54(61)55(73)38(3)78-59)33-51-53(58(75)77-5)50(71)35-60(76,81-51)34-47(69)30-45(67)28-43(65)26-42(64)27-44(66)29-46(68)32-52(72)80-57(36)37(2)20-25-41(63)31-49(70)39-21-23-40(62-4)24-22-39/h6-19,21-24,36-38,41-43,45-48,50-51,53-57,59,62-65,67-69,71,73-74,76H,20,25-35,61H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t36?,37?,38-,41?,42?,43?,45?,46?,47?,48?,50?,51?,53?,54+,55-,56+,57?,59+,60?/m0/s1

HIDE SMILES / InChI

Molecular Formula C60H88N2O19
Molecular Weight 1141.3427
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 5 / 19
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Long-term therapy of benign prostatic hyperplasia. Our experience].
2001 Mar
[Mepartricine and prostatitis. Clinical experience and rationale for use].
2001 Sep
Role of mepartricin in category III chronic nonbacterial prostatitis/chronic pelvic pain syndrome: a randomized prospective placebo-controlled trial.
2004 Jan
Effects of mepartricin, a polyene macrolide antibiotic, on estrogen-induced hyperplastic growth of the dorsolateral prostate and seminal vesicle in immature castrated rats.
2005
Antifungal chemical compounds identified using a C. elegans pathogenicity assay.
2007 Feb
Chronic prostatitis.
2008 May 22
Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.
2009 Sep 14
Substance Class Chemical
Created
by admin
on Sat Dec 16 00:30:50 GMT 2023
Edited
by admin
on Sat Dec 16 00:30:50 GMT 2023
Record UNII
L13V8793FQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEPARTRICIN A
MI  
Common Name English
GEDAMYCIN METHYL ESTER
Common Name English
PARTRICIN A METHYL ESTER
Common Name English
CANDICIDIN D, 40-DEMETHYL-3,7-DIDEOXO-3,7-DIHYDROXY-N47-METHYL-5-OXO-, METHYL ESTER, CYCLIC 15,19-HEMIACETAL
Common Name English
MEPARTRICIN A [MI]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
263-584-8
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
MERCK INDEX
m7184
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY Merck Index
FDA UNII
L13V8793FQ
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
EPA CompTox
DTXSID40872304
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
CAS
62534-68-3
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY
PUBCHEM
76969110
Created by admin on Sat Dec 16 00:30:50 GMT 2023 , Edited by admin on Sat Dec 16 00:30:50 GMT 2023
PRIMARY