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Details

Stereochemistry RACEMIC
Molecular Formula C17H17N.ClH
Molecular Weight 271.785
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BERBINE HYDROCHLORIDE

SMILES

Cl.C1CC2=CC=CC=C2C3CC4=CC=CC=C4CN13

InChI

InChIKey=LTHAWQZXDKSDMD-UHFFFAOYSA-N
InChI=1S/C17H17N.ClH/c1-2-7-15-12-18-10-9-13-5-3-4-8-16(13)17(18)11-14(15)6-1;/h1-8,17H,9-12H2;1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Ring expansions of tetrahydroprotoberberines and related dibenzo[c,g]azecines modulate the dopamine receptor subtype affinity and selectivity.
2010-04
Global Expression Patterns of Three Festuca Species Exposed to Different Doses of Glyphosate Using the Affymetrix GeneChip Wheat Genome Array.
2009
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
2008-07-01
Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction.
2008-06
Alkaloids from Corydalis saxicola and their anti-hepatitis B virus activity.
2008-05
[A story of discoveries in tetrahydroprotoberberines research].
2007-07
Recent developments in studies of l-stepholidine and its analogs: chemistry, pharmacology and clinical implications.
2007
Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigation.
2007
Biphasic firing response of nucleus accumbens neurons elicited by THPB-18 and its correlation with DA receptor subtypes.
2004-12
Thermodynamic study on the effects of beta-cyclodextrin inclusion with berberine.
2002-01-15
Patents

Patents

Name Type Language
(±)-BERBINE HYDROCHLORIDE
Preferred Name English
BERBINE HYDROCHLORIDE
Systematic Name English
6H-DIBENZO(A,G)QUINOLIZINE, 5,8,13,13A-TETRAHYDRO-, HYDROCHLORIDE (1:1)
Systematic Name English
BERBIN HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
FDA UNII
KJ4K5N4UK1
Created by admin on Mon Mar 31 23:24:22 GMT 2025 , Edited by admin on Mon Mar 31 23:24:22 GMT 2025
PRIMARY
CAS
5956-61-6
Created by admin on Mon Mar 31 23:24:22 GMT 2025 , Edited by admin on Mon Mar 31 23:24:22 GMT 2025
PRIMARY
PUBCHEM
85862745
Created by admin on Mon Mar 31 23:24:22 GMT 2025 , Edited by admin on Mon Mar 31 23:24:22 GMT 2025
PRIMARY