Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H17N.ClH |
| Molecular Weight | 271.785 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.C1CC2=CC=CC=C2C3CC4=CC=CC=C4CN13
InChI
InChIKey=LTHAWQZXDKSDMD-UHFFFAOYSA-N
InChI=1S/C17H17N.ClH/c1-2-7-15-12-18-10-9-13-5-3-4-8-16(13)17(18)11-14(15)6-1;/h1-8,17H,9-12H2;1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C17H17N |
| Molecular Weight | 235.3236 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Ring expansions of tetrahydroprotoberberines and related dibenzo[c,g]azecines modulate the dopamine receptor subtype affinity and selectivity. | 2010-04 |
|
| Global Expression Patterns of Three Festuca Species Exposed to Different Doses of Glyphosate Using the Affymetrix GeneChip Wheat Genome Array. | 2009 |
|
| Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. | 2008-07-01 |
|
| Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction. | 2008-06 |
|
| Alkaloids from Corydalis saxicola and their anti-hepatitis B virus activity. | 2008-05 |
|
| [A story of discoveries in tetrahydroprotoberberines research]. | 2007-07 |
|
| Recent developments in studies of l-stepholidine and its analogs: chemistry, pharmacology and clinical implications. | 2007 |
|
| Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigation. | 2007 |
|
| Biphasic firing response of nucleus accumbens neurons elicited by THPB-18 and its correlation with DA receptor subtypes. | 2004-12 |
|
| Thermodynamic study on the effects of beta-cyclodextrin inclusion with berberine. | 2002-01-15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:24:22 GMT 2025
by
admin
on
Mon Mar 31 23:24:22 GMT 2025
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| Record UNII |
KJ4K5N4UK1
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| Record Status |
Validated (UNII)
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| Record Version |
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KJ4K5N4UK1
Created by
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5956-61-6
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85862745
Created by
admin on Mon Mar 31 23:24:22 GMT 2025 , Edited by admin on Mon Mar 31 23:24:22 GMT 2025
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