MEFENOREX

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H18ClN
Molecular Weight	211.731
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEFENOREX

Structure Search

SMILES

CC(CC1=CC=CC=C1)NCCCCl

InChI

InChIKey=XXVROGAVTTXONC-UHFFFAOYSA-N

InChI=1S/C12H18ClN/c1-11(14-9-5-8-13)10-12-6-3-2-4-7-12/h2-4,6-7,11,14H,5,8-10H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3743406
Curator's Comment: description was created based on several sources, including, http://ec.europa.eu/health/documents/community-register/2000/200003093430/anx_3430_en.pdf

Mefenorex or (+/-)N-(3-chloropropyl)-1-methyl-2-phenylethylamine is an N-alkylated analogue of amphetamine. The therapeutic efficacy of mefenorex as an adjunctive support in the treatment of obesity for limited periods of time, as well as its ability to be well tolerated, has been amply demonstrated. Mefenorex is considered to be racemic mixture, no available data regarding enantiospecific pharmacological activity of the compound.

CNS Activity

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578
Unknown 2578
Obesity 203 Sources: https://www.ncbi.nlm.nih.gov/pubmed/37853 https://www.ncbi.nlm.nih.gov/pubmed/3743406	Curative		Withdrawn	Pondinil Approved Use Adjunctive therapy to diet, in patients with obesity and a body mass index (BMI) of 30 kg/m2 or higher who have not responded to an appropriate weight-reducing regimen alone Launch Date 1970

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

40 mg/day

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

MEFENOREX

Official Name

English

MEFENOREX [MI]

Common Name

English

N-(3-CHLOROPROPYL)-.ALPHA.-METHYLPHENETHYLAMINE

Systematic Name

English

mefenorex [INN]

Common Name

English

PHENETHYLAMINE, N-(3-CHLOROPROPYL)-.ALPHA.-METHYL-

Systematic Name

English

Mefenorex [WHO-DD]

Common Name

English

BENZENEETHANAMINE, N-(3-CHLOROPROPYL)-.ALPHA.-METHYL

Common Name

English

Classification Tree Code System Code

WHO-ATC

A08AA09

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

NCI_THESAURUS

C29728

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

DEA NO.

1580

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WHO-VATC

QA08AA09

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

Code System Code Type Description

MERCK INDEX

m7140

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Merck Index

ChEMBL

CHEMBL2110962

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MESH

C000450

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ECHA (EC/EINECS)

241-279-0

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EPA CompTox

DTXSID6057665

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EVMPD

SUB08706MIG

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CAS

17243-57-1

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RXCUI

29444

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RxNorm

DRUG BANK

DB13852

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PUBCHEM

21777

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INN

2494

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NCI_THESAURUS

C83915

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

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DRUG CENTRAL

1664

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

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WIKIPEDIA

MEFENOREX

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

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SMS_ID

100000081459

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

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FDA UNII

K98M4N387W

Created by admin on Fri Dec 15 17:19:58 GMT 2023 , Edited by admin on Fri Dec 15 17:19:58 GMT 2023

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ACTIVE MOIETY


					K98M4N387W

MEFENOREX

SALT/SOLVATE (PARENT)


					6X1N18AU15

MEFENOREX HYDROCHLORIDE