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Details

Stereochemistry RACEMIC
Molecular Formula C19H20N2O4S
Molecular Weight 372.438
Optical Activity ( + / - )
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LERIGLITAZONE

SMILES

CC(O)C1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1

InChI

InChIKey=OXVFDZYQLGRLCD-UHFFFAOYSA-N
InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11-12,17,22H,8-10H2,1H3,(H,21,23,24)

HIDE SMILES / InChI

Description

Hydroxypioglitazone (M-IV) is an active metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone. Experiments in vitro have shown that hydroxypioglitazone was more efficient than the parent drug in stimulating lipid synthesis.

Approval Year

Unknown
149,124

PubMed

ACTIVE MOIETY
Structure of LERIGLITAZONE
PARENT (METABOLITE ACTIVE)
Structure of PIOGLITAZONE
SALT/SOLVATE (PARENT)
Structure of LERIGLITAZONE HYDROCHLORIDE
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