3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H14FN2O7P
Molecular Weight	324.1995
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE

Structure Search

SMILES

CC1=CN([C@H]2C[C@H](F)[C@@H](COP(O)(O)=O)O2)C(=O)NC1=O

InChI

InChIKey=GGCAVPJXJISBOA-XLPZGREQSA-N

InChI=1S/C10H14FN2O7P/c1-5-3-13(10(15)12-9(5)14)8-2-6(11)7(20-8)4-19-21(16,17)18/h3,6-8H,2,4H2,1H3,(H,12,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19433557 | https://www.thepharmaletter.com/article/heidelberg-s-fosalvudine-to-enter-ph-ii

Heidelberg Pharma Research developed fosalvudine tidoxil, a prodrug derived from the nucleoside reverse transcriptase inhibitor alovudine, for the treatment of HIV infections. This drug had reached phase II clinical trials before its development was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug.	2009-07	19433557

Name

Type

Language

5'-THYMIDYLIC ACID, 3'-DEOXY-3'-FLUORO-

Preferred Name

English

3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE

Systematic Name

English

3'-FLUORO-3'-DEOXYTHYMIDINE 5'-PHOSPHATE

Systematic Name

English

URIDINE, 2',3'-DIDEOXY-3'-FLUORO-5-METHYL-, 5'-(DIHYDROGEN PHOSPHATE)

Common Name

English

3'-DEOXY-3'-FLUOROTHYMIDINE MONOPHOSPHATE

Systematic Name

English

Code System Code Type Description

FDA UNII

K6W0IAP44B

Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025

PRIMARY

DRUG BANK

DB03195

Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025

PRIMARY

PUBCHEM

447405

Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025

PRIMARY

CAS

25520-83-6

Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025

PRIMARY

ACTIVE MOIETY


					K6W0IAP44B

3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/19433557 | https://www.thepharmaletter.com/article/heidelberg-s-fosalvudine-to-enter-ph-ii

Originator

Approval Year

PubMed

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19433557 | https://www.thepharmaletter.com/article/heidelberg-s-fosalvudine-to-enter-ph-ii