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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H14FN2O7P
Molecular Weight 324.1995
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE

SMILES

CC1=CN([C@H]2C[C@H](F)[C@@H](COP(O)(O)=O)O2)C(=O)NC1=O

InChI

InChIKey=GGCAVPJXJISBOA-XLPZGREQSA-N
InChI=1S/C10H14FN2O7P/c1-5-3-13(10(15)12-9(5)14)8-2-6(11)7(20-8)4-19-21(16,17)18/h3,6-8H,2,4H2,1H3,(H,12,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

HIDE SMILES / InChI
Molecular Formula C10H14FN2O7P
Molecular Weight 324.1995
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Heidelberg Pharma Research developed fosalvudine tidoxil, a prodrug derived from the nucleoside reverse transcriptase inhibitor alovudine, for the treatment of HIV infections. This drug had reached phase II clinical trials before its development was discontinued.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug.
2009-07
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:28:15 GMT 2025
Edited
by admin
on Mon Mar 31 21:28:15 GMT 2025
Record UNII
K6W0IAP44B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5'-THYMIDYLIC ACID, 3'-DEOXY-3'-FLUORO-
Preferred Name English
3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE
Systematic Name English
3'-FLUORO-3'-DEOXYTHYMIDINE 5'-PHOSPHATE
Systematic Name English
URIDINE, 2',3'-DIDEOXY-3'-FLUORO-5-METHYL-, 5'-(DIHYDROGEN PHOSPHATE)
Common Name English
3'-DEOXY-3'-FLUOROTHYMIDINE MONOPHOSPHATE
Systematic Name English
Code System Code Type Description
FDA UNII
K6W0IAP44B
Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025
PRIMARY
DRUG BANK
DB03195
Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025
PRIMARY
PUBCHEM
447405
Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025
PRIMARY
CAS
25520-83-6
Created by admin on Mon Mar 31 21:28:15 GMT 2025 , Edited by admin on Mon Mar 31 21:28:15 GMT 2025
PRIMARY
Related Record Type Details
Structure of 3'-FLUORO-3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE
ACTIVE MOIETY
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