Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C13H21NO3 |
| Molecular Weight | 239.3107 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=CC=C1OC[C@@H](O)CNC(C)C
InChI
InChIKey=LFTFGCDECFPSQD-NSHDSACASA-N
InChI=1S/C13H21NO3/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3/h4-7,10-11,14-15H,8-9H2,1-3H3/t11-/m0/s1
Levomoprolol (L-moprolol) is a beta-adrenergic blocker which was introduced as an oral medication for treatment of systemic hypertension. It was found to be effective in 2% eyedrops in reducing the intraocular pressure in glaucoma. Observations on glaucoma patients treated with the eyedrop for 1.5 to 2.5 years was without undesirable side effects. L-moprolol and dipivefrin had an equivalent effect in lowering the intraocular pressure. The association of the two drugs caused a further reduction of intraocular pressure.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Tolerability of high doses of (-)-moprolol in healthy volunteers. | 1982 |
|
| [Effects of acute administration of the levogyral beta-blocker levomoprolol on the exercise test in angina pectoris]. | 1984 Dec |
|
| A new catalyst for the asymmetric Henry reaction: synthesis of β-nitroethanols in high enantiomeric excess. | 2012 Dec 21 |
Patents
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29576
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K4NON6FSON
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100000082279
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CHEMBL2106030
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SUB08480MIG
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77164-20-6
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3981
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m1207
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6150
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DTXSID301016500
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3034006
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Levomoprolol
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C83877
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C009976
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ACTIVE MOIETY
