GUAIMESAL

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H14O5
Molecular Weight	286.2794
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(OC2(C)OC(=O)C3=C(O2)C=CC=C3)C=CC=C1

InChI

InChIKey=PSVDIHULUCLEJE-UHFFFAOYSA-N

InChI=1S/C16H14O5/c1-16(20-14-10-6-5-9-13(14)18-2)19-12-8-4-3-7-11(12)15(17)21-16/h3-10H,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2663163

Guaimesal was studied for the treatment of exacerbated chronic bronchitis

Approval Year

PubMed

Title	Date	PubMed
[Clinical evaluation of the therapeutic efficacy of a new antiphlogistic and mucus-regulating drug, guaimesal, in acute and chronic bronchopneumopathies].	1984 Sep 15	6238760
[Guaimesal capsules in the treatment of exacerbated chronic bronchitis].	1984 Sep 30	6238767
Double-blind, placebo-controlled clinical evaluation of guaimesal in outpatients.	1989 May-Jun	2663163
Gas chromatographic-tandem mass spectrometric determination of acetylsalicylic acid in human plasma after oral administration of low-dose aspirin and guaimesal.	1998 May 8	9653928

Patents

Sample Use Guides

In Vivo Use Guide

One hundred and forty outpatients, males and females aged 14 to 70 years, with acute febrile bronchitis, afebrile chronic bronchitis, or flares of chronic bronchitis were treated for seven days with one soft gelatin capsule (500 mg) of guaimesal thrice daily or matching placebo

Route of Administration: Oral

Name

Type

Language

GUAIMESAL

Official Name

English

(±)-2-(O-METHOXYPHENOXY)-2-METHYL-1,3-BENZODIOXAN-4-ONE

Common Name

English

guaimesal [INN]

Common Name

English

GUAIMESAL [MART.]

Common Name

English

Guaimesal [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257