U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C16H14O5
Molecular Weight 286.2794
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GUAIMESAL

SMILES

COC1=C(OC2(C)OC(=O)C3=C(O2)C=CC=C3)C=CC=C1

InChI

InChIKey=PSVDIHULUCLEJE-UHFFFAOYSA-N
InChI=1S/C16H14O5/c1-16(20-14-10-6-5-9-13(14)18-2)19-12-8-4-3-7-11(12)15(17)21-16/h3-10H,1-2H3

HIDE SMILES / InChI
Guaimesal was studied for the treatment of exacerbated chronic bronchitis

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

One hundred and forty outpatients, males and females aged 14 to 70 years, with acute febrile bronchitis, afebrile chronic bronchitis, or flares of chronic bronchitis were treated for seven days with one soft gelatin capsule (500 mg) of guaimesal thrice daily or matching placebo
Route of Administration: Oral
Name Type Language
GUAIMESAL
INN   MART.   WHO-DD  
INN  
Official Name English
(±)-2-(O-METHOXYPHENOXY)-2-METHYL-1,3-BENZODIOXAN-4-ONE
Common Name English
guaimesal [INN]
Common Name English
GUAIMESAL [MART.]
Common Name English
Guaimesal [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C257
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
Code System Code Type Description
SMS_ID
100000084243
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105115
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
PRIMARY
INN
5366
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
PRIMARY
DRUG CENTRAL
1337
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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PUBCHEM
71250
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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MESH
C043484
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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FDA UNII
K43273G1CW
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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NCI_THESAURUS
C65824
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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CAS
81674-79-5
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
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EVMPD
SUB07975MIG
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID00868622
Created by admin on Fri Dec 15 17:34:28 GMT 2023 , Edited by admin on Fri Dec 15 17:34:28 GMT 2023
PRIMARY