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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H28N6O6
Molecular Weight 484.505
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MAZOKALIM

SMILES

CCOC(=O)CCCN1N=NN=C1C2=CC3=C(OC(C)(C)[C@@](C)(O)[C@@H]3OC4=NNC(=O)C=C4)C=C2

InChI

InChIKey=NMOVZVDTGJSEMC-OFNKIYASSA-N
InChI=1S/C23H28N6O6/c1-5-33-19(31)7-6-12-29-21(26-27-28-29)14-8-9-16-15(13-14)20(23(4,32)22(2,3)35-16)34-18-11-10-17(30)24-25-18/h8-11,13,20,32H,5-7,12H2,1-4H3,(H,24,30)/t20-,23+/m1/s1

HIDE SMILES / InChI

Description

Mazokalim is a potassium channel agonist. It was studied in the treatment of asthma and hypertension.

Originator

Approval Year

Unknown
139594
Name Type Language
MAZOKALIM
INN  
INN  
Official Name English
mazokalim [INN]
Common Name English
ETHYL 5-((3S,4R)-4-((1,6-DIHYDRO-6-OXO-3-PYRIDAZINYL)OXY)-3-HYDROXY-2,2,3-TRIMETHYL-6-CHROMANYL)-1H-TETRAZOLE-1-BUTYRATE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C270
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2105166
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
NCI_THESAURUS
C83907
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
EVMPD
SUB08658MIG
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
CAS
164178-54-5
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
PUBCHEM
3045404
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
SMS_ID
100000081748
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
INN
7510
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
FDA UNII
K3N608EC7L
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
EPA CompTox
DTXSID20167720
Created by admin on Sat Dec 16 15:50:14 GMT 2023 , Edited by admin on Sat Dec 16 15:50:14 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of MAZOKALIM
NIH
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