MAZOKALIM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C23H28N6O6
Molecular Weight	484.505
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)CCCN1N=NN=C1C2=CC3=C(OC(C)(C)[C@@](C)(O)[C@@H]3OC4=NNC(=O)C=C4)C=C2

InChI

InChIKey=NMOVZVDTGJSEMC-OFNKIYASSA-N

InChI=1S/C23H28N6O6/c1-5-33-19(31)7-6-12-29-21(26-27-28-29)14-8-9-16-15(13-14)20(23(4,32)22(2,3)35-16)34-18-11-10-17(30)24-25-18/h8-11,13,20,32H,5-7,12H2,1-4H3,(H,24,30)/t20-,23+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C23H28N6O6
Molecular Weight	484.505
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://adisinsight.springer.com/drugs/800009113 | http://apps.who.int/medicinedocs/es/d/Js4895e/6.html

Mazokalim is a potassium channel agonist. It was studied in the treatment of asthma and hypertension.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 06:52:13 GMT 2025` Edited by `admin` on `Wed Apr 02 06:52:13 GMT 2025`
Record UNII	K3N608EC7L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

mazokalim [INN]

Preferred Name

English

MAZOKALIM

Official Name

English

ETHYL 5-((3S,4R)-4-((1,6-DIHYDRO-6-OXO-3-PYRIDAZINYL)OXY)-3-HYDROXY-2,2,3-TRIMETHYL-6-CHROMANYL)-1H-TETRAZOLE-1-BUTYRATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270