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Details

Stereochemistry ABSOLUTE
Molecular Formula C29H36O15
Molecular Weight 624.5871
Optical Activity UNSPECIFIED
Defined Stereocenters 11 / 11
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL HESPERIDIN

SMILES

COC1=CC=C(C=C1OC)[C@@H]2CC(=O)C3=C(O)C=C(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)C=C3O2

InChI

InChIKey=GUMSHIGGVOJLBP-SLRPQMTOSA-N
InChI=1S/C29H36O15/c1-11-22(32)24(34)26(36)28(41-11)40-10-20-23(33)25(35)27(37)29(44-20)42-13-7-14(30)21-15(31)9-17(43-19(21)8-13)12-4-5-16(38-2)18(6-12)39-3/h4-8,11,17,20,22-30,32-37H,9-10H2,1-3H3/t11-,17-,20+,22-,23+,24+,25-,26+,27+,28+,29+/m0/s1

HIDE SMILES / InChI

Description

Methyl hesperidin is a flavanone-type flavonoid and a methylated derivative of hesperidin. It exhibits better bioactivities and water-solubility than hesperidin. It could improve the permeability and integrity of the capillary lining and usually found in association with vitamin C to enhance its effect.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
In a preclinical study, mice were treated with dietary concentrations of 0, 1.25 or 5% for 96 weeks.
Route of Administration: Oral
In Vitro Use Guide
In a fluorescence titration experiment, 2.0 ml solution containing an appropriate concentration of BSA was titrated manually by successive addition of a 10(-3) mol/L solution of methyl hesperidin (to give a final concentration of 5*10(-6) mol/L to 4.76*10(-5) mol/L).