| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H14F3N3O6S |
| Molecular Weight | 457.38 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)NC(=O)N(C1=O)C2=CC=C(OC3=CC=C(C=C3)S(=O)(=O)C(F)(F)F)C(C)=C2
InChI
InChIKey=VBUNOIXRZNJNAD-UHFFFAOYSA-N
InChI=1S/C18H14F3N3O6S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)30-12-4-6-13(7-5-12)31(28,29)18(19,20)21/h3-9H,1-2H3,(H,22,25,26)
Ponazuril, sold by the Bayer Corporation under the trade name Marquis, was the first FDA-approved treatment for equine protozoal myeloencephalitis (EPM) in horse, caused by Sarcocystis neurona. Also this drug was used in animals such as cats, dogs against coccidia, an intestinal parasite. Coccidia treatment is far shorter than treatment for EPM.
Approval Year
PubMed
Patents
Sample Use Guides
horses: paste to treat one 1,200 lb (544 kg) horse for seven days, at a dose rate of 5 mg/kg (2.27 mg/lb) body weight
Route of Administration:
Oral
ACTIVE MOIETY
PARENT (METABOLITE)
