Ziclumeran

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

NTLA-2001 component mRNA000042

Preferred Name

English

Ziclumeran

Official Name

English

messenger RNA (mRNA), 5' capped, encoding codon-optimised clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9), flanked by untranslated regions (UTR) with significant sequence homology to the Xenopus beta globin

Common Name

English

ZICLUMERAN [USAN]

Common Name

English

RNA (recombinant 5?-(m7Gm-(5??5?)-ppp-G)-capped all uridine?N1-methylpseudouridine-substituted synthetic CRISPR-associated endodeoxyribonuclease CAS9 low codon A-optimized-specifying plus Xenopus laevis ?-globin 5?-and 3?-untranslated flanking region-con

Common Name

English

ziclumeran [INN]

Common Name

English

cas9 mRNA (mRNA000042)

Common Name

English

cas9 mRNA

Common Name

English

Code System Code Type Description

USAN

MN-129

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

FDA UNII

JJ5AS2HL3G

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

CAS

2305431-29-0

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

SMS_ID

300000023313

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

NCI_THESAURUS

C203205

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

INN

12328

Created by admin on Wed Apr 02 14:31:32 GMT 2025 , Edited by admin on Wed Apr 02 14:31:32 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_4423	4423 / 4423

Linkage	Site Range	Site Count
Phosphate	1_2-1_4423	4422 / 4422

ACTIVE MOIETY


					JJ5AS2HL3G