Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C27H31NO3 |
| Molecular Weight | 417.5399 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(CCN(C)C(CCC3=CC=CC=C3)CC4=C2C(O)=C(OC)C=C4)C=C1
InChI
InChIKey=IORHSKBXWWSQME-UHFFFAOYSA-N
InChI=1S/C27H31NO3/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3
Asocainol is a rather efficient antiarrhythmic agent that has the effects of both class Ia and class IV antiarrhythmic drugs. Asocainol interfere with the sodium channel and lengthens the action potential. Besides that, Asocainol decreases conduction through the AV node, and shorten phase two (the plateau) of the cardiac action potential. Asocainol reduce the contractility of the heart, so may be inappropriate in heart failure. Asocainol is an effective antiarrhythmic agent in a variety of animal arrhythmia models and species.
Approval Year
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Preferred Name | English | ||
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Official Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C47793
Created by
admin on Mon Mar 31 18:38:26 GMT 2025 , Edited by admin on Mon Mar 31 18:38:26 GMT 2025
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5092
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SUB05583MIG
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C042287
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C72574
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CHEMBL2104050
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ASOCAINOL
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J40338OKKT
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77400-65-8
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71161
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100000086608
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DTXSID90868434
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ACTIVE MOIETY
