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Details

Stereochemistry ACHIRAL
Molecular Formula C30H38N4.2C2H4O2
Molecular Weight 574.7534
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINDECAMINE ACETATE ANHYDROUS

SMILES

CC(O)=O.CC(O)=O.CC1=CC(NCCCCCCCCCCNC2=CC(C)=NC3=C2C=CC=C3)=C4C=CC=CC4=N1

InChI

InChIKey=KJLDLEIBEQIBFL-UHFFFAOYSA-N
InChI=1S/C30H38N4.2C2H4O2/c1-23-21-29(25-15-9-11-17-27(25)33-23)31-19-13-7-5-3-4-6-8-14-20-32-30-22-24(2)34-28-18-12-10-16-26(28)30;2*1-2(3)4/h9-12,15-18,21-22H,3-8,13-14,19-20H2,1-2H3,(H,31,33)(H,32,34);2*1H3,(H,3,4)

HIDE SMILES / InChI
Quindecamine (also known as UCL-1407) is quinaldine derivative with antibiotic and fungicidal activity. Treatment of rats and mice with Quindecamine (250 mg/kg/ day) each day for 4 weeks followed by 500 mg/kg/day for 2 more weeks reduced spontaneous motility and body weight but produced no pathological abnormalities of the various organs studied. In vitro, the drug showed very good activity against Staphylococcus aureus, Streptococcus hemolyticus, Candida albicans, Trichophyton mentagrophytes, and T. vaginalis. The drug had very good activity in 180 human subjects with various bacterial and mycotic diseases of the skin and mucosa when applied as a 1% salve.

Originator

Sources: JP40028465

Approval Year

PubMed

PubMed

TitleDatePubMed
Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channels.
2000 Apr
Patents

Patents

Name Type Language
QUINDECAMINE ACETATE ANHYDROUS
Common Name English
QUINDECAMINE DIACETATE
Common Name English
1,10-DECANEDIAMINE, N,N'-BIS(2-METHYL-4-QUINOLINYL)-, DIACETATE
Systematic Name English
Code System Code Type Description
PUBCHEM
64739
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
CAS
19146-62-4
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID80940778
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
FDA UNII
J3Y36BPX1R
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY