Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H17Br2NO2.ClH |
| Molecular Weight | 415.549 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.O[C@H]1CC[C@@H](CC1)NCC2=CC(Br)=CC(Br)=C2O
InChI
InChIKey=BGRWLVRJIPTKQW-PFWPSKEQSA-N
InChI=1S/C13H17Br2NO2.ClH/c14-9-5-8(13(18)12(15)6-9)7-16-10-1-3-11(17)4-2-10;/h5-6,10-11,16-18H,1-4,7H2;1H/t10-,11-;
DescriptionCurator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/3363832 | http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500013623.pdf
Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/3363832 | http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500013623.pdf
Dembrexine is a mucolytic agent which reduces the viscosity of respiratory mucus. It improves movement of mucus in small airways. Dembrexine increases secretion of the serous cells in the glands of the nasal, tracheal and bronchial cells and in type II alveolar cells. It also possesses an anti-tussive effect. Dembrexine is used in the treatment of respiratory disease in horses. All respiratory infections with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection of the upper airways.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0043129 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe drug is indicated for the treatment of respiratory disease in horses. All respiratory infections
with increased secretions. Acute, sub-acute bronchitis. Chronic respiratory disease. Infection
of the upper airways. |
|||
| Palliative | Sputolosin Approved UseThe agent is indicated for the treatment of foal pneumonia. |
| Name | Type | Language | ||
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Preferred Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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WHO-VATC |
QR05CB90
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admin on Mon Mar 31 19:21:56 GMT 2025 , Edited by admin on Mon Mar 31 19:21:56 GMT 2025
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19381318
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DTXSID70967151
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52702-51-9
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300000029158
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J32Z420496
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admin on Mon Mar 31 19:21:56 GMT 2025 , Edited by admin on Mon Mar 31 19:21:56 GMT 2025
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ACTIVE MOIETY
SUBSTANCE RECORD
