FRENLOSIRSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

ION-251 FREE ACID

Preferred Name

English

FRENLOSIRSEN

Official Name

English

DNA, D(P-THIO)((2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA.-L-MANNOFURANO)A-(3'->4')-(2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA.-L-MANNOFURANO)G-T-T-G-T-A-A-A-T-G-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL)

Systematic Name

English

ION251 FREE ACID

Code

English

Frenlosirsen [WHO-DD]

Common Name

English

frenlosirsen [INN]

Common Name

English

ALL-P-AMBO-2'-O,4'-C-((S)-ETHYLIDENE)-P-THIOADENYLYL-(3'-O->5-O)-2'-O,4'-C-((S)-ETHYLIDENE)-P-THIOGUANYLYL-(3'-O->5'-O)-P-THIOTHYMIDYLYL-(3'-O->5'-O)-P-THIOTHYMIDYLYL-(3'-O->5'-O)-2'-DEOXY-P-THIOGUANYLYL-(3'-O->5'-O)-P-THIOTHYMIDYLYL-(3'-O->5'-O)-2'-DEOX

Systematic Name

English

FRENLOSIRSEN [USAN]

Common Name

English

ION-935918 FREE ACID

Code

English

Code System Code Type Description

CAS

2304711-81-5

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

USAN

HI-04

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

SMS_ID

300000039065

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

NCI_THESAURUS

C173725

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

FDA UNII

J2Y9QT3BWL

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

INN

11520

Created by admin on Wed Apr 02 06:32:31 GMT 2025 , Edited by admin on Wed Apr 02 06:32:31 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
	1_1-1_2;1_15-1_16	4 / 16
Deoxyribose (DNA)	1_3-1_11	9 / 16
2'-O-Methoxyethyl ribose	1_12-1_14	3 / 16

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_16	15 / 15

ACTIVE MOIETY


					J2Y9QT3BWL