U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C23H35N3O
Molecular Weight 369.5435
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACTISOMIDE

SMILES

[H][C@]12CCCCN1C(C)=NC(=O)[C@]2(CCN(C(C)C)C(C)C)C3=CC=CC=C3

InChI

InChIKey=QAHRRCMLXFLZTF-FYYLOGMGSA-N
InChI=1S/C23H35N3O/c1-17(2)25(18(3)4)16-14-23(20-11-7-6-8-12-20)21-13-9-10-15-26(21)19(5)24-22(23)27/h6-8,11-12,17-18,21H,9-10,13-16H2,1-5H3/t21-,23-/m1/s1

HIDE SMILES / InChI
ACTISOMIDE is a class 1A/1B antiarrhythmic agent. It blocks sodium channels in a manner similar to lidocaine and mexiletine. It is a well-tolerated, effective agent against both atrial and ventricular arrhythmias.

Approval Year

PubMed

PubMed

TitleDatePubMed
Name Type Language
ACTISOMIDE
INN   USAN  
INN   USAN  
Official Name English
SC 36602
Code English
3H-PYRIDO(1,2-C)PYRIMIDIN-3-ONE, 4-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-4,4A,5,6,7,8-HEXAHYDRO-1-METHYL-4-PHENYL-, CIS-(±)-
Common Name English
(±)-CIS-4-(2-(DIISOPROPYLAMINO)ETHYL)-4,4A,5,6,7,8-HEXAHYDRO-1-METHYL-4-PHENYL-3H-PYRIDO(1,2-C)PYRIMIDIN-3-ONE
Common Name English
actisomide [INN]
Common Name English
ACTISOMIDE [USAN]
Common Name English
SC-36602
Code English
Classification Tree Code System Code
NCI_THESAURUS C47793
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
Code System Code Type Description
SMS_ID
100000087678
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
ChEMBL
CHEMBL286259
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
NCI_THESAURUS
C90662
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
FDA UNII
IJQ29N87NR
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
USAN
X-83
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
WIKIPEDIA
Actisomide
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
PUBCHEM
6917898
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
EVMPD
SUB05257MIG
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
INN
5944
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
EPA CompTox
DTXSID001026019
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY
CAS
96914-39-5
Created by admin on Fri Dec 15 15:10:03 GMT 2023 , Edited by admin on Fri Dec 15 15:10:03 GMT 2023
PRIMARY