| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H17NO4 |
| Molecular Weight | 287.3105 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H]1C=C2CCN3CC4=CC5=C(OCO5)C=C4[C@@H]([C@@H]23)[C@@H]1O
InChI
InChIKey=XGVJWXAYKUHDOO-DANNLKNASA-N
InChI=1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15+,16+/m0/s1
Lycorine is a natural pyrrolo[de]phenanthridine ring-type alkaloid extracted from Amaryllidaceae. It has been reported to exhibit a wide range of physiological effects, including anti-viral, anti-malarial, anti-cancer and anti-inflammatory. Although a defined target or mechanism of action of lycorine is still unknown, it is a candidate anti-inflammatory and anti-cancer drug.
CNS Activity
Approval Year
PubMed
Patents
Sample Use Guides
In a preclinical study, mice were given lycorine at 5 mg/kg/day or 10 mg/kg/day.
Route of Administration:
Intraperitoneal
SUBSTANCE RECORD
