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Approval Year

Unknown
149124
Name Type Language
IMO-2125
Preferred Name English
TILSOTOLIMOD SODIUM
USAN  
Official Name English
TLR9 AGONIST IMO-2125
Code English
O,O'-(2-HYDROXYPROPANE-1,3-DIYL) BIS (ALL-P-AMBO-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-2'-DEOXY-7-CARBA-P-THIOGUANYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-2'-D
Systematic Name English
TILSOTOLIMOD SODIUM [USAN]
Common Name English
5-HYDROXY-2-DEOXY-P-THIOTHYMIDYLYL-(3->5)-2-DEOXY- P-THIOCYTIDYLYL-(3->5)-2-DEOXY-P-THIO-7-DEAZA-GUANYLYL- (3->5)-2-DEOXY-P-THIOADENYLYL-(3->5)-2-DEOXY-PTHIOADENYLYL-( 3->5)-2-DEOXY-P-THIOCYTIDYLYL-(3->5)- 2-DEOXY-P-THIO-7-DEAZA-GUANYLYL-(3->5)-2DEOXY-PT
Systematic Name English
IMO-2125 SODIUM
Code English
DNA, D(P-THIO)(T-C-C7G-A-A-C-C7G-T-T-C-C7G), 3',3'''-(O,O'-(2-HYDROXY-1,3-PROPANEDIYL) BIS(HYDROGEN PHOSPHOROTHIOATE)), SODIUM SALT (1:22)
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C2139
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
FDA ORPHAN DRUG 571016
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
Code System Code Type Description
CAS
2089768-67-0
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
PRIMARY
FDA UNII
I6CNU8SY0F
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
PRIMARY
NCI_THESAURUS
C125080
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
PRIMARY
USAN
FG-111
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
PRIMARY
SMS_ID
300000011160
Created by admin on Wed Apr 02 00:18:59 GMT 2025 , Edited by admin on Wed Apr 02 00:18:59 GMT 2025
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_1-1_11;2_1-2_11 22 / 22
Linkage Site Range Site Count
Sodium Phosporothioate 1_1-1_10;2_1-2_10 20 / 20
ACTIVE MOIETY
TILSOTOLIMOD
SUBSTANCE RECORD
TILSOTOLIMOD SODIUM
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966