TILSOTOLIMOD

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 13:55:18 GMT 2023` Edited by `admin` on `Sat Dec 16 13:55:18 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	G287IC9MH3
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TILSOTOLIMOD

Official Name

English

O,O'-(2-HYDROXYPROPANE-1,3-DIYL) BIS(HYDROGEN ALL-P-AMBO-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-2'- DEOXY-7-CARBA-P-THIOGUANYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-2'- DEOXY-P-THIOCYTIDYLYL-(3'

Systematic Name

English

DNA, D(P-THIO)(T-C-C7G-A-A-C-C7G-T-T-C-C7G), 3',3'''-(O,O'-(2-HYDROXY-1,3-PROPANEDIYL) BIS(HYDROGEN PHOSPHOROTHIOATE))

Systematic Name

English

TILSOTOLIMOD [USAN]

Common Name

English

Tilsotolimod [WHO-DD]

Common Name

English

tilsotolimod [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129820

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

Code System Code Type Description

CAS

1224565-55-2

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

SUPERSEDED

SMS_ID

300000010544

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

INN

10634

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

CAS

1948266-37-2

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

FDA UNII

G287IC9MH3

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

USAN

FG-110

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

NCI_THESAURUS

C152632

Created by admin on Sat Dec 16 13:55:18 GMT 2023 , Edited by admin on Sat Dec 16 13:55:18 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_11;2_1-2_11	22 / 22

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_10;2_1-2_10	20 / 20

Related Record Type Details


					I6CNU8SY0F

TILSOTOLIMOD SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					G287IC9MH3

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE_SUBSTITUTION	[1_3] [1_7] [2_3] [2_7]	SITE_SPECIFIC			7-DEAZA-2'-DEOXYGUANOSINE	7668FG8W4U
LINKER	[1_11] [2_11]	SITE_SPECIFIC			TILSOTOLIMOD LINKER	RP14X866FH