Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C6H11O7.C4H11NO3.Al.2HO |
Molecular Weight | 377.2786 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[OH-].[OH-].[Al+3].NC(CO)(CO)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O
InChI
InChIKey=GJJYZOBRHIMORS-GQOAHPRESA-K
InChI=1S/C6H12O7.C4H11NO3.Al.2H2O/c7-1-2(8)3(9)4(10)5(11)6(12)13;5-4(1-6,2-7)3-8;;;/h2-5,7-11H,1H2,(H,12,13);6-8H,1-3,5H2;;2*1H2/q;;+3;;/p-3/t2-,3-,4+,5-;;;;/m1..../s1
Aloglutamol is a salt of aluminum, gluconic acid, and tromethamine. Upon administration, the tromethamine interacts with hydrochloric acid and forms hydrochloride, while aluminum gluconate dihydroxide also binds to hydrochloric acid, forming aluminum chloride and free gluconic acid. Due to this chemical reaction, the pH of the stomach does not rise abruptly, so there is no rebound phenomenon. Aloglutamol is marketed worldwide under trade names Altris, Pyreses, Tasto, and Sabro. It is used for the treatment of hyperacidity, esophagitis, gastritis, peptic ulcer, and hiatal hernia.
Approval Year
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Classification Tree | Code System | Code | ||
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WHO-VATC |
QA02AB06
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WHO-ATC |
A02AB06
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17392
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DTXSID601027584
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72941505
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I670EI8M2N
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DB13650
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Aloglutamol
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13755-41-4
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4759
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100000078208
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ACTIVE MOIETY
SUBSTANCE RECORD