ALOGLUTAMOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C6H11O7.C4H11NO3.Al.2HO
Molecular Weight	377.2786
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[OH-].[OH-].[Al+3].NC(CO)(CO)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

InChIKey=GJJYZOBRHIMORS-GQOAHPRESA-K

InChI=1S/C6H12O7.C4H11NO3.Al.2H2O/c7-1-2(8)3(9)4(10)5(11)6(12)13;5-4(1-6,2-7)3-8;;;/h2-5,7-11H,1H2,(H,12,13);6-8H,1-3,5H2;;2*1H2/q;;+3;;/p-3/t2-,3-,4+,5-;;;;/m1..../s1

HIDE SMILES / InChI

Molecular Formula	Al
Molecular Weight	26.9815
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H10NO3
Molecular Weight	120.1271
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H12O7
Molecular Weight	196.1553
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugbank.ca/drugs/DB13650 | https://mx.prvademecum.com/medicamento/sabro-2793/

Aloglutamol is a salt of aluminum, gluconic acid, and tromethamine. Upon administration, the tromethamine interacts with hydrochloric acid and forms hydrochloride, while aluminum gluconate dihydroxide also binds to hydrochloric acid, forming aluminum chloride and free gluconic acid. Due to this chemical reaction, the pH of the stomach does not rise abruptly, so there is no rebound phenomenon. Aloglutamol is marketed worldwide under trade names Altris, Pyreses, Tasto, and Sabro. It is used for the treatment of hyperacidity, esophagitis, gastritis, peptic ulcer, and hiatal hernia.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:53:03 GMT 2023` Edited by `admin` on `Sat Dec 16 08:53:03 GMT 2023`
Record UNII	I670EI8M2N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALOGLUTAMOL

Common Name

English

DIHYDROXYALUMINUM GLUCONATE, TRIS(HYDROXYMETHYL)AMINOMETHANE (1:1)

Systematic Name

English

ALTRIS

Brand Name

English

Aloglutamol [WHO-DD]

Common Name

English

SABRO

Brand Name

English

TASTO

Brand Name

English

PYRESES

Brand Name

English

Classification Tree Code System Code

WHO-VATC

QA02AB06