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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H11O7.C4H11NO3.Al.2HO
Molecular Weight 377.2786
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALOGLUTAMOL

SMILES

[OH-].[OH-].[Al+3].NC(CO)(CO)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

InChIKey=GJJYZOBRHIMORS-GQOAHPRESA-K
InChI=1S/C6H12O7.C4H11NO3.Al.2H2O/c7-1-2(8)3(9)4(10)5(11)6(12)13;5-4(1-6,2-7)3-8;;;/h2-5,7-11H,1H2,(H,12,13);6-8H,1-3,5H2;;2*1H2/q;;+3;;/p-3/t2-,3-,4+,5-;;;;/m1..../s1

HIDE SMILES / InChI

Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H10NO3
Molecular Weight 120.1271
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H12O7
Molecular Weight 196.1553
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Aloglutamol is a salt of aluminum, gluconic acid, and tromethamine. Upon administration, the tromethamine interacts with hydrochloric acid and forms hydrochloride, while aluminum gluconate dihydroxide also binds to hydrochloric acid, forming aluminum chloride and free gluconic acid. Due to this chemical reaction, the pH of the stomach does not rise abruptly, so there is no rebound phenomenon. Aloglutamol is marketed worldwide under trade names Altris, Pyreses, Tasto, and Sabro. It is used for the treatment of hyperacidity, esophagitis, gastritis, peptic ulcer, and hiatal hernia.

Approval Year

Substance Class Chemical
Record UNII
I670EI8M2N
Record Status Validated (UNII)
Record Version