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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H11O7.C4H11NO3.Al.2HO
Molecular Weight 377.2786
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALOGLUTAMOL

SMILES

[OH-].[OH-].[Al+3].NC(CO)(CO)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

InChIKey=GJJYZOBRHIMORS-GQOAHPRESA-K
InChI=1S/C6H12O7.C4H11NO3.Al.2H2O/c7-1-2(8)3(9)4(10)5(11)6(12)13;5-4(1-6,2-7)3-8;;;/h2-5,7-11H,1H2,(H,12,13);6-8H,1-3,5H2;;2*1H2/q;;+3;;/p-3/t2-,3-,4+,5-;;;;/m1..../s1

HIDE SMILES / InChI
Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C4H10NO3
Molecular Weight 120.1271
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C6H12O7
Molecular Weight 196.1553
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Aloglutamol is a salt of aluminum, gluconic acid, and tromethamine. Upon administration, the tromethamine interacts with hydrochloric acid and forms hydrochloride, while aluminum gluconate dihydroxide also binds to hydrochloric acid, forming aluminum chloride and free gluconic acid. Due to this chemical reaction, the pH of the stomach does not rise abruptly, so there is no rebound phenomenon. Aloglutamol is marketed worldwide under trade names Altris, Pyreses, Tasto, and Sabro. It is used for the treatment of hyperacidity, esophagitis, gastritis, peptic ulcer, and hiatal hernia.

Approval Year

Unknown
139594
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:53:03 UTC 2023
Edited
by admin
on Sat Dec 16 08:53:03 UTC 2023
Record UNII
I670EI8M2N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALOGLUTAMOL
WHO-DD  
Common Name English
DIHYDROXYALUMINUM GLUCONATE, TRIS(HYDROXYMETHYL)AMINOMETHANE (1:1)
Systematic Name English
ALTRIS
Brand Name English
Aloglutamol [WHO-DD]
Common Name English
SABRO
Brand Name English
TASTO
Brand Name English
PYRESES
Brand Name English
Classification Tree Code System Code
WHO-VATC QA02AB06
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
WHO-ATC A02AB06
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
Code System Code Type Description
RXCUI
17392
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID601027584
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
PUBCHEM
72941505
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
FDA UNII
I670EI8M2N
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
DRUG BANK
DB13650
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
WIKIPEDIA
Aloglutamol
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
CAS
13755-41-4
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
EVMPD
SUB12794MIG
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
ChEMBL
CHEMBL3707300
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
DRUG CENTRAL
4759
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
SMS_ID
100000078208
Created by admin on Sat Dec 16 08:53:03 UTC 2023 , Edited by admin on Sat Dec 16 08:53:03 UTC 2023
PRIMARY
Related Record Type Details
Structure of DIHYDROXYALUMINUM GLUCONATE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of DIHYDROXYALUMINUM GLUCONATE
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