Imdusiran Sodium

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

Imdusiran Sodium

Official Name

English

AB-729

Preferred Name

English

IMDUSIRAN SODIUM [USAN]

Common Name

English

RNA, (Gm-sp-Um-sp-Gm-Cm-(2?-deoxy-2?-fluoro)A-(2?-deoxy-2?-fluoro)C-(2?-deoxy-2?-fluoro)U-Um-Cm-Gm-Cm-Um-Um-Cm-Am-Cm-Am), 3?-[[[rel-(3S,4R)]-1-(9-carboxy-1-oxononyl)-4-(hydroxymethyl)-3,4-dimethyl-3-pyrrolidinyl]methyl hydrogen phosphate], carboxamide wi

Common Name

English

[1-(10-{[(S)-1,5-Bis({2-[(3,5-bis{[2-(2-{2-[(2-acetamido-2-deoxy-?-D-galactopyranosyl)oxy]ethoxy}ethoxy)ethyl]carbamoyl}phenyl)amino]-2-oxoethyl}amino)-1,5-dioxopentan-2-yl]amino}-10-oxodecanoyl)-4-(hydroxymethyl)-3,4-dimethylpyrrolidin-3-yl]methyl all-P

Common Name

English

Code System Code Type Description

CAS

2826248-50-2

Created by admin on Wed Apr 02 11:22:11 GMT 2025 , Edited by admin on Wed Apr 02 11:22:11 GMT 2025

PRIMARY

NCI_THESAURUS

C203141

Created by admin on Wed Apr 02 11:22:11 GMT 2025 , Edited by admin on Wed Apr 02 11:22:11 GMT 2025

PRIMARY

SMS_ID

300000051686

Created by admin on Wed Apr 02 11:22:11 GMT 2025 , Edited by admin on Wed Apr 02 11:22:11 GMT 2025

PRIMARY

FDA UNII

HX4CRZ94FC

Created by admin on Wed Apr 02 11:22:11 GMT 2025 , Edited by admin on Wed Apr 02 11:22:11 GMT 2025

PRIMARY

USAN

LM-91

Created by admin on Wed Apr 02 11:22:11 GMT 2025 , Edited by admin on Wed Apr 02 11:22:11 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-Fluoro-Ribose	1_2;1_14;1_16;2_5-2_7	6 / 39
2'-O-Methyl-Ribose	1_1;1_3-1_13;1_15;1_17-1_21;2_1-2_4;2_8-2_17	32 / 39
D-Ribose (RNA)	1_22	1 / 39

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_3;1_20-1_21;2_2-2_3	6 / 37
	1_4-1_19;1_22;2_4-2_17	31 / 37

SUBSTANCE RECORD


					HX4CRZ94FC

Imdusiran Sodium