DICTAMNINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H9NO2
Molecular Weight	199.2054
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

COC1=C2C=CC=CC2=NC3=C1C=CO3

InChI

InChIKey=WIONIXOBNMDJFJ-UHFFFAOYSA-N

InChI=1S/C12H9NO2/c1-14-11-8-4-2-3-5-10(8)13-12-9(11)6-7-15-12/h2-7H,1H3

HIDE SMILES / InChI

Description

Dictamnine, a furoquinoline alkaloid isolated from the root bark of Dictamnus dasycarpus Turcz. (Rutaceae) is reported to have a wide range of pharmacological activities. Dictamnine is a strong mutagen and phototoxic alkaloid with DNA as a cellular target.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
DNA 282	Binding Agent 1,076

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2,596

PubMed

PubMed

Show entries

Title	Date	PubMed
Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine.	2002 Jul	12141852
Feeding deterrents from Dictamnus dasycarpus Turcz against two stored-product insects.	2002 Mar 13	11879018
Plants traditionally prescribed to treat tazo (malaria) in the eastern region of Madagascar.	2003 Jul 24	12921540
A new prenylated arylnaphthalene lignan from Haplophyllum myrtifolium.	2003 Sep	12946719
cis-Dihydrodiol, arene oxide and phenol metabolites of dictamnine: key intermediates in the biodegradation and biosynthesis of furoquinoline alkaloids.	2005 Aug 21	16075095

Showing 1 to 5 of 10 entries

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Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Show entries

Name

Type

Language

DICTAMNINE

Common Name

English

DICTAMINE

Preferred Name

English

DICTAMNINE [MI]

Common Name

English

4-METHOXYFURO(2,3-B)QUINOLINE

Systematic Name

English

Showing 1 to 4 of 4 entries

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Show entries

Code System

Code

Type

Description

PUBCHEM

68085

PRIMARY

CAS

484-29-7

PRIMARY

FDA UNII

HQZ3798D0A

PRIMARY

MERCK INDEX

m4369

PRIMARY

Merck Index

EPA CompTox

DTXSID0041012

PRIMARY

Showing 1 to 5 of 6 entries

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SUBSTANCE RECORD


					HQZ3798D0A

DICTAMNINE