Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H9NO2 |
| Molecular Weight | 199.2054 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2C=CC=CC2=NC3=C1C=CO3
InChI
InChIKey=WIONIXOBNMDJFJ-UHFFFAOYSA-N
InChI=1S/C12H9NO2/c1-14-11-8-4-2-3-5-10(8)13-12-9(11)6-7-15-12/h2-7H,1H3
| Molecular Formula | C12H9NO2 |
| Molecular Weight | 199.2054 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: DNA Sources: https://www.ncbi.nlm.nih.gov/pubmed/7104872 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Dermatopharmacokinetic studies of liangfu cream in mice skin]. | 2010-09 |
|
| [Simultaneous determination of three active compounds in root barks of Dictamnus dasycarpus by RP-HPLC]. | 2010-01 |
|
| [Effects of penetration enhancers on in vitro percutaneous absorption and amount retained in skin of paeonol, dictamnine, fraxinellone and glycyrrhetinic acid in Liangfu cream]. | 2009-07 |
|
| Isolation of secondary metabolites from Hortia oreadica (Rutaceae) leaves through high-speed counter-current chromatography. | 2009-05-08 |
|
| Alkaloids from the roots of Zanthoxylum nitidum and their antiviral and antifungal effects. | 2008-09 |
|
| Global gene expression profile of Saccharomyces cerevisiae induced by dictamnine. | 2008-09 |
|
| Constituents of the root wood of Zanthoxylum wutaiense with antitubercular activity. | 2008-07 |
|
| Effective biotic elicitation of Ruta graveolens L. shoot cultures by lysates from Pectobacterium atrosepticum and Bacillus sp. | 2008-03 |
|
| Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors. | 2007-12-07 |
|
| A survey of Chinese herbal ingredients with liver protection activities. | 2007-05-10 |
|
| Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen. | 2006-08 |
|
| Pressurized liquid extraction followed by high-performance liquid chromatography for determination of seven active compounds in Cortex Dictamni. | 2006-03-10 |
|
| [Studies on chemical constituents in bark of dictamnus dasycarpus]. | 2005-11 |
|
| cis-Dihydrodiol, arene oxide and phenol metabolites of dictamnine: key intermediates in the biodegradation and biosynthesis of furoquinoline alkaloids. | 2005-08-21 |
|
| Furoquinoline alkaloids from the southern African Rutaceae Teclea natalensis. | 2005-03 |
|
| A new prenylated arylnaphthalene lignan from Haplophyllum myrtifolium. | 2003-09 |
|
| Plants traditionally prescribed to treat tazo (malaria) in the eastern region of Madagascar. | 2003-07-24 |
|
| Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. | 2002-07 |
|
| Feeding deterrents from Dictamnus dasycarpus Turcz against two stored-product insects. | 2002-03-13 |
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7104872
Curator's Comment: In vitro, labeled dictamnine was shown to form covalent monoadducts with purified DNA from M. hiemalis in the presence of long-wave ultraviolet light.
Unknown
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:57:37 GMT 2025
by
admin
on
Mon Mar 31 19:57:37 GMT 2025
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| Record UNII |
HQZ3798D0A
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| Record Status |
Validated (UNII)
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| Record Version |
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