U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C10H12N4O4
Molecular Weight 252.2267
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2'-DEOXYINOSINE

SMILES

OC[C@H]1O[C@H](C[C@@H]1O)N2C=NC3=C2N=CNC3=O

InChI

InChIKey=VGONTNSXDCQUGY-RRKCRQDMSA-N
InChI=1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
UVB-specific regulation of gene expression in human melanocytic cells: cell cycle effects and implication in the generation of melanoma.
1998 Nov 9
Mutation identification DNA analysis system (MIDAS) for detection of known mutations.
1999 Jun
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
1999 Jun 10
Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.
2001
Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo.
2001 Dec
Sequencing in the presence of betaine: Improvement in sequencing of the localized repeat sequence regions.
2002 Dec
Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function.
2003 Feb 25
Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
2004 Sep
Quantitative gas chromatography mass spectrometric analysis of 2'-deoxyinosine in tissue DNA.
2006
Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2.
2006
Biochemical retrosynthesis of 2'-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase.
2006 Aug
Clastogenic factors as potential biomarkers of increased superoxide production.
2007 Dec 11
In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulation.
2007 Oct 8
Discovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approach.
2007 Sep 6
Self-Avoiding Molecular Recognition Systems (SAMRS).
2008
Efficient recognition of an unpaired lesion by a DNA repair glycosylase.
2009 Dec 16
Potential short-term use of oral cladribine in treatment of relapsing-remitting multiple sclerosis.
2010 Oct 5
Patents
Name Type Language
2'-DEOXYINOSINE
Systematic Name English
DEOXYINOSINE
Common Name English
9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE [WHO-IP]
Systematic Name English
HYPOXANTHINE DEOXYRIBOSIDE
Systematic Name English
9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE
Systematic Name English
HYPOXANTHINE, 9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-
Systematic Name English
DIDANOSINE IMPURITY C [EP IMPURITY]
Common Name English
2'-DEOXYINOSINE [WHO-IP]
Common Name English
2'-DEOXYINOSINE [USP IMPURITY]
Systematic Name English
DIDANOSINE IMPURITY C
EP  
Common Name English
INOSINE, 2'-DEOXY-
Systematic Name English
6H-PURIN-6-ONE, 9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,9-DIHYDRO-
Systematic Name English
Code System Code Type Description
PUBCHEM
135398593
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY
CHEBI
28997
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY
CAS
890-38-0
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY
DRUG BANK
DB02380
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY
ECHA (EC/EINECS)
212-964-1
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY
FDA UNII
HN0RQ6SBWQ
Created by admin on Sat Dec 16 03:27:50 GMT 2023 , Edited by admin on Sat Dec 16 03:27:50 GMT 2023
PRIMARY