Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H28ClN3O2.CH4O3S |
| Molecular Weight | 510.046 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(O)(=O)=O.COC1=C2CCC(=O)N(CCCN3CCN(CC3)C4=CC=CC(Cl)=C4)C2=CC=C1
InChI
InChIKey=LAYQZXHSBQXCFR-UHFFFAOYSA-N
InChI=1S/C23H28ClN3O2.CH4O3S/c1-29-22-8-3-7-21-20(22)9-10-23(28)27(21)12-4-11-25-13-15-26(16-14-25)19-6-2-5-18(24)17-19;1-5(2,3)4/h2-3,5-8,17H,4,9-16H2,1H3;1H3,(H,2,3,4)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors. | 2007-01 |
|
| In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors. | 2005-07-11 |
|
| Behavioral pharmacology of sigma-ligands. | 2004-11 |
|
| Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus. | 2004-08 |
|
| Potential antidepressant activity of sigma ligands. | 2003-09-30 |
|
| Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate). | 2002-04 |
|
| Antidepressant-like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523. | 2001-12 |
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H9J1LZ3AAH
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260369-93-5
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DBSALT002835
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9892539
Created by
admin on Mon Mar 31 21:34:01 GMT 2025 , Edited by admin on Mon Mar 31 21:34:01 GMT 2025
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ACTIVE MOIETY
PARENT (SALT/SOLVATE)
