Zinc stearate

US Previously Marketed

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C18H35O2.Zn
Molecular Weight	632.348
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Zn++].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O

InChI

InChIKey=XOOUIPVCVHRTMJ-UHFFFAOYSA-L

InChI=1S/2C18H36O2.Zn/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2

HIDE SMILES / InChI

Description
Sources: https://www.pharmacompass.com/chemistry-chemical-name/zinc-stearate | https://www.drugs.com/inactive/zinc-stearate-63.html | http://www.akrochem.com/pdf/product/stearates/zinc_stearate_powder.pdf | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.8994

Zinc stearate is a mild antiseptic and astringent, and it has been used as a local soothing application for inflammatory and irritating skin diseases. Zinc stearate is primarily used in pharmacuetical formulations as a lubricant in tablet and capsule manufacture at concentrations up to 1.5% w/w. It is a protective agent used in powders and ointments in the treatment of eczema, acne, and other skin diseases. GRAS - Zinc stearate complies with FDA Standard CFR 21 sections 177.2600, 182.8994 and 178.2010.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Chronic kidney disease 56 Sources: https://www.drugs.com/inactive/zinc-stearate-63.html	Inactive ingredient		Approved 8429	RENVELA Approved Use Renvela® is a phosphate binder indicated for the control of serum phosphorus in adults and children 6 years of age and older with chronic kidney disease on dialysis. Launch Date 2000
Periodontitis 23 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22975500	Primary		Preclinical	Unknown Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
AA Blocks	AA003VBI	https://www.aablocks.com/goods/Goods/detail?id=AA003VBI
AK Scientific, Inc. (AKSCI)	R391	http://www.aksci.com/item_detail.php?cat=R391
Aaron Chemicals	AR003W3A	http://www.aaronchem.com/557-05-1
Achemica	ACMC-20aj8a	http://www.achemica.com/prodinfo/?id=137993
Achemtek	0104-016545	http://www.achemtek.com/557-05-1
Acros Organics	AC263780200	https://www.fishersci.com/shop/products/zinc-stearate-acros-organics-3/AC263780200
Acros Organics	AC263780010	https://www.fishersci.com/shop/products/zinc-stearate-acros-organics/AC263780010
Acros Organics	AC263780050	https://www.fishersci.com/shop/products/zinc-stearate-acros-organics/AC263780050
Alfa Aesar	33238	https://www.alfa.com/en/catalog/033238/
Alichem	450002555	http://www.alichem.com/en/products/557-05-1.html
Ambeed	A243623	https://www.ambeed.com/products/557-05-1.html
Avantor Inc	101187-710	https://us.vwr.com/store/catalog/product.jsp?catalog_number=101187-710
Avantor Inc	200039-174	https://us.vwr.com/store/product/7518234/zinc-stearate
BLD Pharm	BD157247	http://www.bldpharm.com/products/557-05-1.html
ChemMol	49427814	http://www.chemmol.com/chemmol/49427814.html
Finetech	FT-0645152	http://www.finetechnology-ind.com/prod/detail/pub/557-05-1.html
Mittal Dhatu Rashayan Udyog	Zinc Stearate Zinc Octadecanoate Zinc distearate Rashayan Zinc Stearate	http://www.rashayan.com/products.html
MolPort	MolPort-006-111-836	https://www.molport.com/shop/molecule-link/MolPort-006-111-836
MuseChem	R071314	https://www.musechem.com/product/R071314.html
Parchem	667	http://www.parchem.com/chemical-supplier-distributor/Zinc-Stearate-001428.aspx
Renno Tech	RL04105	http://www.rennotech.com/product_show.asp?id=3715
VladaChem	VL145123	https://www.vladachem.com/product.php?products=557-05-1
VladaChem	VL167299	https://www.vladachem.com/product.php?products=557-05-1
iChemical	EBD45338	http://www.ichemical.com/chemicals/cas-557-05-1

PubMed

Title	Date	PubMed
Estrogenic potency of food-packaging-associated plasticizers and antioxidants as detected in ERalpha and ERbeta reporter gene cell lines.	2006 Jun 14	16756374
Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats.	2012	22975500
Revealing the Nature and Distribution of Metal Carboxylates in Jackson Pollock's Alchemy (1947) by Micro-Attenuated Total Reflection FT-IR Spectroscopic Imaging.	2017 Jan 17	28035811

Patents

Sample Use Guides

In Vivo Use Guide

Rats: intramuscularly injected suspension containing Zinc stearate (0.6mg as zinc) in 0.2mL of corn oil on around the alveolar bone once a week for 12 weeks

Route of Administration: Intramuscular

In Vitro Use Guide

For a typical synthesis of ZCIS NCs, CuI (0.2 mmol), In(Ac)3 (0.2 mmol), zinc stearate (Zn(SA)2) (0.1 mmol) and OA (1.0 mmol) were mixed with 1.0 mL of DDT and 8.0 mL of ODE in a 50 mL four-neck flask under argon atmosphere and magnetic stirring.

Name

Type

Language

Zinc stearate

Official Name

English

ZINC STEARATE [USP MONOGRAPH]

Common Name

English

ZINC STEARATE [II]

Common Name

English

OCTADECANOIC ACID, ZINC SALT

Common Name

English

ZINC STEARATE [EP MONOGRAPH]

Common Name

English

ZINC STEARATE [HSDB]

Common Name

English

Zinc stearate [WHO-DD]

Common Name

English

ZINC STEARATE [MART.]

Common Name

English

ZINC STEARATE [USP-RS]

Common Name

English

ZINC STEARATE [VANDF]

Common Name

English

ZINC STEARATE [INCI]

Common Name

English

ZINC STEARATE [MI]

Common Name

English

NSC-25957

Code

English

Classification Tree Code System Code

EPA PESTICIDE CODE

77002