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Details

Stereochemistry ACHIRAL
Molecular Formula C12H14N2.2ClH
Molecular Weight 259.175
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE

SMILES

Cl.Cl.NCCNC1=C2C=CC=CC2=CC=C1

InChI

InChIKey=MZNYWPRCVDMOJG-UHFFFAOYSA-N
InChI=1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
48.0 nM [Ki]
58.0 nM [Ki]
61.0 nM [Ki]
PubMed

PubMed

TitleDatePubMed
Validation of a CE assay for the analysis of isomeric aminopyridines and diaminopyridines.
2001 Feb
Sensitive spectrophotometric determination of nitrite in human saliva and rain water and of nitrogen dioxide in the atmosphere.
2001 Jan-Feb
Determination of nitrite by sequential injection analysis of electrokinetic flow analysis system.
2002 Mar 11
Diagnostic value of protein induced by vitamin K absence (PIVKAII) and hepatoma-specific band of serum gamma-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to alpha-fetoprotein.
2003 Jun 16
[Evaluation of a colorimetric method for studying the interaction between microorganisms and intestinal epithelial cells].
2003 Oct-Dec
Flow-injection simultaneous determination of selenium(IV) and selenium(IV + VI) using photooxidative coupling of p-hydrazinobensenesulfonic acid with N-(1-naphthyl)ethylenediamine.
2004 Dec 15
Determination of mimosine by a sensitive indirect spectrophotometric method.
2004 Jun 17
[Highly sensitive spectrofluorimetric determination of trace amounts of nitrite with N-(1-naphthyl) ethylenediamine].
2005 Aug
Studies of selenium in environmental samples and synthetic mixtures by spectrophotometry.
2006 Feb
Spectrophotometric determination of V(V) in environmental, biological, pharmaceutical and alloy samples by novel oxidative coupling reactions.
2007 Feb 9
Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp.
2007 Jun
Application of genomic biomarkers to predict increased lung tumor incidence in 2-year rodent cancer bioassays.
2007 May
Effects of nebulized ketamine on allergen-induced airway hyperresponsiveness and inflammation in actively sensitized Brown-Norway rats.
2007 May 4
Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats.
2008 Aug 9
Rosiglitazone inhibits metastasis development of a murine mammary tumor cell line LMM3.
2008 Feb 8
Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro.
2008 Jun 13
Development and validation of spectrophotometric methods for determination of ceftazidime in pharmaceutical dosage forms.
2008 Sep
Digestive proteolytic activity in the Sunn pest, Eurygaster integriceps.
2009
Purification and characterization of a lectin from Phaseolus vulgaris cv. (Anasazi beans).
2009
Pro-inflammatory and oxidative stress pathways which compromise sperm motility and survival may be altered by L-carnitine.
2009 Apr-Jun
Liquid-phase microextraction and fibre-optics-based cuvetteless CCD-array micro-spectrophotometry for trace analysis.
2009 Aug 26
Nitric oxide bioavailability and its potential relevance to the variation in susceptibility to the renal and vascular complications in patients with type 2 diabetes.
2009 Jan
Anti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of Providencia and San Andrés (SW Caribbean).
2009 Mar 10
Antiulcer activity of fluvoxamine in rats and its effect on oxidant and antioxidant parameters in stomach tissue.
2009 May 20
Immunostimulatory Effects of Cordyceps militaris on Macrophages through the Enhanced Production of Cytokines via the Activation of NF-kappaB.
2010 Apr
The Ca2+ activated SK3 channel is expressed in microglia in the rat striatum and contributes to microglia-mediated neurotoxicity in vitro.
2010 Jan 14
Tetrahydroabietic Acid, a Reduced Abietic Acid, Inhibits the Production of Inflammatory Mediators in RAW264.7 Macrophages Activated with Lipopolysaccharide.
2010 Mar
Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata.
2010 May 11
EGb761 protects motoneurons against avulsion-induced oxidative stress in rats.
2010 May 24
Patents

Patents

Name Type Language
N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE
MI  
Systematic Name English
REAGENTS, BRATTON-MARSHALL
Brand Name English
N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE [MI]
Common Name English
N-(1-NAPTHYL)ETHYLENE DIAMINE DIHYDROCHLORIDE [HSDB]
Common Name English
NSC-9849
Code English
N-NAPHTHYLETHYLENEDIAMINE DIHYDROCHLORIDE
Systematic Name English
ETHYLENEDIAMINE, N-1-NAPHTHYL-, DIHYDROCHLORIDE
Common Name English
1,2-ETHANEDIAMINE, N-1-NAPHTHALENYL-, DIHYDROCHLORIDE
Common Name English
BRATTON-MARSHALL REAGENT
Brand Name English
1,2-ETHANEDIAMINE, N1-1-NAPHTHALENYL-, HYDROCHLORIDE (1:2)
Systematic Name English
Code System Code Type Description
NSC
9849
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
MERCK INDEX
m7761
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY Merck Index
HSDB
2877
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
MESH
C008588
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
CAS
1465-25-4
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
ECHA (EC/EINECS)
215-981-2
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
FDA UNII
H734599KJL
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
EPA CompTox
DTXSID8020917
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY
PUBCHEM
15106
Created by admin on Fri Dec 15 17:45:16 UTC 2023 , Edited by admin on Fri Dec 15 17:45:16 UTC 2023
PRIMARY