CYCLOPHENAZINE HYDROCHLORIDE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H26F3N3S.2ClH
Molecular Weight	506.455
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CYCLOPHENAZINE HYDROCHLORIDE

SMILES

Cl.Cl.FC(F)(F)C1=CC2=C(SC3=C(C=CC=C3)N2CCCN4CCN(CC4)C5CC5)C=C1

InChI

InChIKey=PGFVMQPOOFLBBI-UHFFFAOYSA-N

InChI=1S/C23H26F3N3S.2ClH/c24-23(25,26)17-6-9-22-20(16-17)29(19-4-1-2-5-21(19)30-22)11-3-10-27-12-14-28(15-13-27)18-7-8-18;;/h1-2,4-6,9,16,18H,3,7-8,10-15H2;2*1H

HIDE SMILES / InChI

Description

Cyclophenazine is an antagonist of dopamine receptors, discovered by Eli Lilly. The drug is claimed to possess tranquilizing, anti-emetic action, and is able to potentiate the action of anticholinergic compounds in inhibiting the gastric secretion.

Originator

Approval Year

PubMed

Show entries

Title	Date	PubMed
Central dopamine receptors mediating pergolide-induced elevation of serum corticosterone in rats. Characterization by the use of antagonists.	1984 Dec	6527743

Showing 1 to 1 of 1 entries

Previous1Next

Patents

Show entries

Name

Type

Language

CYCLOPHENAZINE HYDROCHLORIDE

Official Name

English

CYCLOPHENAZINE HCL

Common Name

English

10-[3-(4-Cyclopropyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride

Systematic Name

English

CICLOFENAZINE HYDROCHLORIDE

Common Name

English

10H-PHENOTHIAZINE, 10-(3-(4-CYCLOPROPYL-1-PIPERAZINYL)PROPYL)-2-(TRIFLUOROMETHYL)-, DIHYDROCHLORIDE

Common Name

English

Showing 1 to 5 of 6 entries

Previous1 2Next

Show entries

Classification Tree

Code System

Code

Agent Affecting Nervous System

NCI_THESAURUS

C29710

Showing 1 to 1 of 1 entries

Previous1Next

Show entries

Code System

Code

Type

Description

CAS

15686-74-5

PRIMARY

ChEMBL

CHEMBL2110782

PRIMARY

PUBCHEM

168895

PRIMARY

FDA UNII

H68VTK0LL9

PRIMARY

NCI_THESAURUS

C81587

PRIMARY

Showing 1 to 5 of 5 entries

Previous1Next

PARENT (SALT/SOLVATE)


					OH4ZJ36RB2

CYCLOPHENAZINE

SUBSTANCE RECORD


					H68VTK0LL9

CYCLOPHENAZINE HYDROCHLORIDE