CYCLOPHENAZINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H26F3N3S.2ClH
Molecular Weight	506.455
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CYCLOPHENAZINE HYDROCHLORIDE

Structure Search

SMILES

Cl.Cl.FC(F)(F)C1=CC2=C(SC3=C(C=CC=C3)N2CCCN4CCN(CC4)C5CC5)C=C1

InChI

InChIKey=PGFVMQPOOFLBBI-UHFFFAOYSA-N

InChI=1S/C23H26F3N3S.2ClH/c24-23(25,26)17-6-9-22-20(16-17)29(19-4-1-2-5-21(19)30-22)11-3-10-27-12-14-28(15-13-27)18-7-8-18;;/h1-2,4-6,9,16,18H,3,7-8,10-15H2;2*1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C23H26F3N3S
Molecular Weight	433.533
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6527743 | https://patents.google.com/patent/US3342816A/en

Cyclophenazine is an antagonist of dopamine receptors, discovered by Eli Lilly. The drug is claimed to possess tranquilizing, anti-emetic action, and is able to potentiate the action of anticholinergic compounds in inhibiting the gastric secretion.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:18:57 GMT 2023` Edited by `admin` on `Fri Dec 15 15:18:57 GMT 2023`
Record UNII	H68VTK0LL9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYCLOPHENAZINE HYDROCHLORIDE

Official Name

English

CYCLOPHENAZINE HCL

Common Name

English

10-[3-(4-Cyclopropyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride

Systematic Name

English

CICLOFENAZINE HYDROCHLORIDE

Common Name

English

10H-PHENOTHIAZINE, 10-(3-(4-CYCLOPROPYL-1-PIPERAZINYL)PROPYL)-2-(TRIFLUOROMETHYL)-, DIHYDROCHLORIDE

Common Name

English

CYCLOPHENAZINE HYDROCHLORIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710