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Details

Stereochemistry ABSOLUTE
Molecular Formula C11H18N2O3S
Molecular Weight 258.337
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BIOTIN METHYL ESTER

SMILES

[H][C@]12CS[C@@H](CCCCC(=O)OC)[C@@]1([H])NC(=O)N2

InChI

InChIKey=BHEWJAXNLVWPSC-NRPADANISA-N
InChI=1S/C11H18N2O3S/c1-16-9(14)5-3-2-4-8-10-7(6-17-8)12-11(15)13-10/h7-8,10H,2-6H2,1H3,(H2,12,13,15)/t7-,8-,10-/m0/s1

HIDE SMILES / InChI
Biotin methyl ester is an intermediate in the synthesis of Biotin. It is used as an inhibitor of biotin transport and uptake in “in vitro” researches. Biotin and its methyl ester are equally active for the growth of yeast (Saccharomyces cerevisiae, strain M). Lactobacillus casei can utilize the methyl ester of biotin. However growth and fermentation are slower than with free biotin.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: N,N′,N′′-tris-(7-methyl-1,8-naphthyridin-2-yl)-1,3,5-benzenetricarboxamide
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
The nitrilase superfamily: classification, structure and function.
2001
Molecular recognition: improved binding of biotin derivatives with synthetic receptors.
2006 Apr 14
Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery.
2006 May-Jun
Biotin reagents for antibody pretargeting. 7. Investigation of chemically inert biotinidase blocking functionalities for synthetic utility.
2006 Nov-Dec
Biotin uptake by rabbit corneal epithelial cells: role of sodium-dependent multivitamin transporter (SMVT).
2006 Oct
Molecular recognition studies on naphthyridine derivatives.
2010 Mar 3
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
1 mM of biotin methyl ester inhibits [3H]Biotin uptake on Primary cultured rabbit corneal epithelial cells by 24%.
Name Type Language
BIOTIN METHYL ESTER
Common Name English
1H-THIENO(3,4-D)IMIDAZOLE-4-PENTANOIC ACID, HEXAHYDRO-2-OXO-, METHYL ESTER, (3AS,4S,6AR)-
Common Name English
BIOTIN, METHYL ESTER
Common Name English
(+)-BIOTIN METHYL ESTER
Common Name English
D-(+)-BIOTIN METHYL ESTER
Common Name English
D-BIOTIN METHYL ESTER
Common Name English
1H-THIENO(3,4-D)IMIDAZOLE-4-PENTANOIC ACID, HEXAHYDRO-2-OXO-, METHYL ESTER, (3AS-(3A.ALPHA.,4.BETA.,6A.ALPHA.))-
Common Name English
Code System Code Type Description
PUBCHEM
83871
Created by admin on Fri Dec 15 18:50:48 GMT 2023 , Edited by admin on Fri Dec 15 18:50:48 GMT 2023
PRIMARY
CAS
608-16-2
Created by admin on Fri Dec 15 18:50:48 GMT 2023 , Edited by admin on Fri Dec 15 18:50:48 GMT 2023
PRIMARY
FDA UNII
H3S7E3P0H6
Created by admin on Fri Dec 15 18:50:48 GMT 2023 , Edited by admin on Fri Dec 15 18:50:48 GMT 2023
PRIMARY
MESH
C411823
Created by admin on Fri Dec 15 18:50:48 GMT 2023 , Edited by admin on Fri Dec 15 18:50:48 GMT 2023
PRIMARY