Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H18N2O3S |
| Molecular Weight | 258.337 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CS[C@@H](CCCCC(=O)OC)[C@@]1([H])NC(=O)N2
InChI
InChIKey=BHEWJAXNLVWPSC-NRPADANISA-N
InChI=1S/C11H18N2O3S/c1-16-9(14)5-3-2-4-8-10-7(6-17-8)12-11(15)13-10/h7-8,10H,2-6H2,1H3,(H2,12,13,15)/t7-,8-,10-/m0/s1
| Molecular Formula | C11H18N2O3S |
| Molecular Weight | 258.337 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Biotin methyl ester is an intermediate in the synthesis of Biotin. It is used as an inhibitor of biotin transport and uptake in “in vitro” researches. Biotin and its methyl ester are equally active for the growth of yeast (Saccharomyces cerevisiae, strain M). Lactobacillus casei can utilize the methyl ester of biotin. However growth and fermentation are slower than with free biotin.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The nitrilase superfamily: classification, structure and function. | 2001 |
|
| Transport of biotin in human keratinocytes. | 2003 Mar |
|
| Towards the design of host-guest complexes: biotin and urea derivatives versus artificial receptors. | 2004 Dec 15 |
|
| Molecular recognition: improved binding of biotin derivatives with synthetic receptors. | 2006 Apr 14 |
|
| Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery. | 2006 May-Jun |
|
| Biotin reagents for antibody pretargeting. 7. Investigation of chemically inert biotinidase blocking functionalities for synthetic utility. | 2006 Nov-Dec |
|
| Biotin uptake by rabbit corneal epithelial cells: role of sodium-dependent multivitamin transporter (SMVT). | 2006 Oct |
|
| Molecular recognition studies on naphthyridine derivatives. | 2010 Mar 3 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:50:48 GMT 2023
by
admin
on
Fri Dec 15 18:50:48 GMT 2023
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| Record UNII |
H3S7E3P0H6
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| Record Status |
Validated (UNII)
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| Record Version |
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83871
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608-16-2
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H3S7E3P0H6
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C411823
Created by
admin on Fri Dec 15 18:50:48 GMT 2023 , Edited by admin on Fri Dec 15 18:50:48 GMT 2023
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