THIOUREA

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH4N2S
Molecular Weight	76.121
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(N)=S

InChI

InChIKey=UMGDCJDMYOKAJW-UHFFFAOYSA-N

InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
In vivo toxicity, pharmacokinetic features and tissue distribution of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236), a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.	2001	11505789
Iron-induced oxidative stress up-regulates calreticulin levels in intestinal epithelial (Caco-2) cells.	2001	11500943
Inhibition of lung natural killer cell activity by smoking: the role of alveolar macrophages.	2001	11416246
Evaluation of nitrification-inhibition measurements.	2001	11379092
[The Na+/Ca2+ exchanger as responsible for myocardial stunning].	2001	11374139
Thiouracil antithyroid drugs as a new class of neuronal nitric oxide synthase inhibitors.	2001 Apr 6	11401533
Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.	2001 Aug	11509490
Inhibition of Na+/Ca2+ exchange with KB-R7943 or bepridil diminished mineral deposition by osteoblasts.	2001 Aug	11499866
Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.	2001 Aug	11487523
Influence of sediment and pore-water composition on nitrite accumulation in a nitrate-perfused freshwater sediment.	2001 Aug	11471681
Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury.	2001 Aug 1	11470463
Cardiac sodium-calcium exchanger: a double-edged sword.	2001 Aug 1	11470457
Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs.	2001 Aug 10	11502280
Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons.	2001 Aug 15	11483237
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent.	2001 Feb 1	11462972
Carbohydrate-based receptors with multiple thiourea binding sites. Multipoint hydrogen bond recognition of dicarboxylates and monosaccharides.	2001 Feb 23	11312968
Thiourea enhances mapping of the proteome from murine white adipose tissue.	2001 Jul	11503206
Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion.	2001 Jul	11485036
A proving of Thiosinamine.	2001 Jul	11479789
Sodium-calcium exchanger (NCX-1) and calcium modulation: NCX protein expression patterns and regulation of early heart development.	2001 Jul	11458386
Chlorotris(N,N'-dicyclohexylthiourea-S)tellurium(II) chloride, a tellurium complex with a TeClS3 coordination sphere.	2001 Jul	11443265
The effect of thiolate organic compounds on methylmercury accumulation and redistribution in sheepshead minnows, Cyprinodon variegatus.	2001 Jul	11434298
Synthesis of plaunotol derivatives and their antibacterial activities against Helicobacter pylori.	2001 Jul	11425580
N-(3-acyloxy-2-benzylpropyl)-N'-dihydroxytetrahydrobenzazepine and tetrahydroisoquinoline thiourea analogues as vanilloid receptor ligands.	2001 Jul	11425572
SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.	2001 Jul	11408549
Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.	2001 Jul 13	11331290
Some 3-thioxo/alkylthio-1,2,4-triazoles with a substituted thiourea moiety as possible antimycobacterials.	2001 Jul 9	11425542
Role of nitric oxide in human gastric cancer cells treated with 5-fluorouracil.	2001 Jul-Aug	11410796
Protein alkylation in the presence/absence of thiourea in proteome analysis: a matrix assisted laser desorption/ionization-time of flight-mass spectrometry investigation.	2001 Jun	11465507
Influence of neutral cyclodextrin concentration on plate numbers in capillary electrophoresis.	2001 Jun	11465494
An immunoblotting method for high-resolution isoelectric focusing of protein isoforms on immobilized pH gradients.	2001 Jun	11465484
Silver ion microplates for immunoassays.	2001 Jun	11414228
Aminoethyl-isothiourea inhibits leukocyte production of reactive oxygen species and proinflammatory cytokines induced by streptococcal cell wall components in human whole blood.	2001 Jun	11386618
Aminoethyl-isothiourea in gram-positive shock: an inhibitor of inducible nitric oxide synthase or a jack-of-all-trades?	2001 Jun	11386617
Aminoethyl-isothiourea inhibits the increase in plasma endothelin-1 caused by serogroup A streptococci and prolongs survival in rat peritoneal sepsis.	2001 Jun	11386616
A novel method of studying wound healing.	2001 Jun 1	11368532
Competitive sorption of platinum and palladium on chitosan derivatives.	2001 Jun 12	11325428
Metamorphosis of summer flounder, Paralichthys dentatus: cell proliferation and differentiation of the gastric mucosa and developmental effects of altered thyroidal status.	2001 Jun 15	11429761
Synthesis and characterization of CdIn(2)S(4) nanorods by converting CdS nanorods via the hydrothermal route.	2001 Jun 18	11399183
Capillary-electrochromatographic separations with copolymeric reversed-stationary phase and ion-exchanger-packed columns.	2001 Jun 22	11453022
Catalysis and inhibition of ligand substitution in palladium(II) square-planar complexes: effects of DNA.	2001 Mar 7	11456812
Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.	2001 May	11325806
The effects of the Na(+)/Ca(++) exchange blocker on osmotic blood-brain barrier disruption.	2001 May 11	11334793
Thiols in coastal waters of the western North Sea and English Channel.	2001 May 15	11393967
Lipopolysaccharide-induced cell cycle arrest in macrophages occurs independently of nitric oxide synthase II induction.	2001 May 28	11389976
Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats.	2001 May 4	11348630
Synthesis of some pyridone derivatives.	2001 May-Jun	11486604
[Synthesis of 1-hydroxyalkyl-3-substituted ureas and thioureas as a substrates for alcohol dehydrogenase].	2001 May-Jun	11443945
Effect of a series of novel sulphonylthioureas on glucose tolerance in the obese fa/fa Zucker rat.	2001 May-Jun	11380511
Combinatorial synthesis of heterocycles: solid-phase synthesis of 6-amino-2,4-dioxo-3,4-dihydro-1,3,5-triazine derivatives.	2001 May-Jun	11350251

Patents

Name

Type

Language

THIOUREA

Official Name

English

THIOUREA [HSDB]

Common Name

English

THIOCARBAMIDE

Common Name

English

THIOUREA [INCI]

Common Name

English

THIOUREA [IARC]

Common Name

English

Thiourea [WHO-DD]

Common Name

English

PROPYLTHIOURACIL IMPURITY A [EP IMPURITY]

Common Name

English

NSC-5033

Code

English

THIOUREA [MI]

Common Name

English

2-THIOUREA

Common Name

English

THIOUREA [VANDF]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 189.190