THIOUREA

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH4N2S
Molecular Weight	76.121
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(N)=S

InChI

InChIKey=UMGDCJDMYOKAJW-UHFFFAOYSA-N

InChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

HIDE SMILES / InChI

Molecular Formula	CH4N2S
Molecular Weight	76.121
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Pretreatment with cationic lipid-mediated transfer of the Na+K+-ATPase pump in a mouse model in vivo augments resolution of high permeability pulmonary oedema.	2000 Jun	10849556
In vivo toxicity, pharmacokinetic features and tissue distribution of N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thiourea (HI-236), a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.	2001	11505789
Iron-induced oxidative stress up-regulates calreticulin levels in intestinal epithelial (Caco-2) cells.	2001	11500943
Inhibition of lung natural killer cell activity by smoking: the role of alveolar macrophages.	2001	11416246
Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system.	2001	11223894
Role of nNOS in regulation of renal function in angiotensin II-induced hypertension.	2001 Aug	11509490
Inhibition of Na+/Ca2+ exchange with KB-R7943 or bepridil diminished mineral deposition by osteoblasts.	2001 Aug	11499866
Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity.	2001 Aug	11487523
Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury.	2001 Aug 1	11470463
Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs.	2001 Aug 10	11502280
The effect of protease inhibitors on the two-dimensional electrophoresis pattern of red blood cell membranes.	2001 Feb	11258769
Puromycin aminonucleoside induces glomerular epithelial cell apoptosis.	2001 Feb	11170791
Pre- or post-ischemic treatment with a novel Na+/Ca2+ exchange inhibitor, KB-R7943, shows renal protective effects in rats with ischemic acute renal failure.	2001 Feb	11160625
Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats.	2001 Feb	11160605
Intestinal ischemia induces late preconditioning against myocardial infarction: a role for inducible nitric oxide synthase.	2001 Feb 1	11164849
N-(3-Acyloxy-2-benzylpropyl)-N'-(4-hydroxy-3-methoxybenzyl) thiourea derivatives as potent vanilloid receptor agonists and analgesics.	2001 Jan	11197340
Functional role of sodium-calcium exchange in the regulation of renal vascular resistance.	2001 Jan	11133525
Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances.	2001 Jan-Feb	11299780
Thiourea enhances mapping of the proteome from murine white adipose tissue.	2001 Jul	11503206
Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion.	2001 Jul	11485036
SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models.	2001 Jul	11408549
Role of nitric oxide in human gastric cancer cells treated with 5-fluorouracil.	2001 Jul-Aug	11410796
Silver ion microplates for immunoassays.	2001 Jun	11414228
Aminoethyl-isothiourea inhibits the increase in plasma endothelin-1 caused by serogroup A streptococci and prolongs survival in rat peritoneal sepsis.	2001 Jun	11386616
Metamorphosis of summer flounder, Paralichthys dentatus: cell proliferation and differentiation of the gastric mucosa and developmental effects of altered thyroidal status.	2001 Jun 15	11429761
Decomposition of alkyl-substituted urea molecules at a hydroxide-bridged dinickel center.	2001 Mar 12	11300826
Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas.	2001 Mar 29	11297455
Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.	2001 May	11325806
Synthesis of some pyridone derivatives.	2001 May-Jun	11486604

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:59:17 GMT 2023` Edited by `admin` on `Fri Dec 15 14:59:17 GMT 2023`
Record UNII	GYV9AM2QAG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

THIOUREA

Official Name

English

THIOUREA [HSDB]

Common Name

English

THIOCARBAMIDE

Common Name

English

THIOUREA [INCI]

Common Name

English

THIOUREA [IARC]

Common Name

English

Thiourea [WHO-DD]

Common Name

English

PROPYLTHIOURACIL IMPURITY A [EP IMPURITY]

Common Name

English

NSC-5033

Code

English

THIOUREA [MI]

Common Name

English

2-THIOUREA

Common Name

English

THIOUREA [VANDF]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 189.190